Comparison of the Outcome of Ventricular Septal Defect Closure using Gore-Tex and Glutaraldehyde-treated Autologous Pericardium
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 3
Abstract
Aim: A comparison of glutaraldehyde-treated autologous pericardium and Gore-Tex patch for closure of ventricular septal defect (VSD). Materials and Methods: Patients undergoing repair for VSD were included in the study. Group 1 used Gore-Tex patch for VSD closure and Group 2 used glutaraldehyde-treated autologous pericardium patch for the VSD closure. Results: Autologous pericardium is easily available, sterile, and non-immune reaction. Fixation in 0.6% glutaraldehyde improves its handling qualities and reduces the risk of aneurysmal dilation. In our experience, the handling characteristics of glutaraldehyde-treated autologous pericardium are better than other materials. We also find that the elastic glutaraldehyde-treated autologous pericardium is more in harmony with septal movements than synthetic prosthetic materials. Moreover, the incidence of infective endocarditis is reduced post-operatively. Conclusion: Glutaraldehyde-treated autologous pericardium is an excellent material for surgical patch closure of VSD. It is easily available and does not require sterilization. Further follow-up is required to assess its long-term efficacy.
Authors and Affiliations
G Josephraj, Vijay Anand, V T Siddharth, B Karthikeyan, P Manivannan, Heber Anandan
Keywords
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