COMPARITIVE STUDY OF MEMORY ENHANCING PROPERTY OF “MODAFINIL AND CISSAMPELOS PARIERA” IN MICE
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 5
Abstract
Piracetam is established learning and memory enhancing agent which have gained entry into the market.Modafinil, a novel wake-promoting agent and Cissampelos pariera , have been reported to have a similar clinical profile. The present study was undertaken to investigate the comparative effect of Modafinil , Piracetam and Cissampelos pariera on learning and memory in mice. Elevated plus maze and passive avoidance paradigm were employed to test learning and memory. Common doses of (200mg/kg.) Piracetam1 Cissampelos pariera and Modafinil were administered for 7 successive days in separate group of animals.
Authors and Affiliations
Prateek Bisht*| Dept. of Pharmaceutical chemistry, T. John College of Pharmacy, Bangalore, Karnataka, India-560042., Rekha. S| Dept. of Pharmaceutical chemistry, T. John College of Pharmacy, Bangalore, Karnataka, India-560042., Chandrashekhara. S| Dept. of Pharmaceutics, M.M College of Pharmacy, Belgaum, Karnataka, India-590016., Vineeth Chandy| Dept. of Pharmaceutical chemistry, T. John College of Pharmacy, Bangalore, Karnataka, India-560042., Prof. Satyanand Tyagi| President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), New Delhi, India-110074.
Keywords
Related Articles
- EP ID EP1383
- DOI -
- Views 526
- Downloads 34
NEW SPECTROPHOTOMETRIC DETERMINATION OFMETOCLOPRAMIDE IN BULK AND PHARMACEUTICAL DOSAGE FORM
The new, selective and sensitive visible spectrophotometric method have been developed for the estimation of Metoclopramide in bulk and in pharmaceutical preparations. The amino group in Metoclopramide is diazotized w...
EVALUATION OF PKD2 GENE (G/C) POLYMORPHISM IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE AMONG SOUTH INDIANS (MADURAI).
Polycystic kidney disease (PKD) is the leading causes of end-stage renal failure (ESRD) and a common indication of dialysis / renal transplantation. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal rece...
Analgesic effect of methanolic extract of Vetiveria zizanoides in wistar rats
Introduction: Vetiveria zizanoides is used as a traditional medicine for a number of conditions, but there is lack of scientific data regarding its analgesic action.Aim: to study the analgesic action of methanolic extrac...
FORMULATION AND EVALUATION OF SUSTAINED RELEASE TABLETS OF MEFENAMIC ACID USING HYDROPHILIC POLYMERS
Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. It has a dose of 250 mg 4 times daily. It has a very short half-life of 2 hours and thus controlling the release woul...
SEROLOGICAL DIAGNOSIS OF HAV AND HEV AND THEIR PREVALENCE IN CLINICALLY SUSPECTED CASES OF ACUTE VIRAL HEPATITIS
NTRODUCTION: ‘Viral Hepatitis’ denotes a primary infection of liver by heterogeneous group of Hepatitis virus. They are clinically indistinguishable, leading to morbidity and mortality. Mainly diagnosed by serological an...