Composite Scaffolds for Bone Tissue Engineering
Journal Title: American Journal of Biochemistry and Biotechnology - Year 2006, Vol 2, Issue 2
Abstract
Biomaterial and scaffold development underpins the advancement of tissue engineering. Traditional scaffolds based on biodegradable polymers such as poly(lactic acid) and poly(lactic acid-co- glycolic acid) are weak and non-osteoconductive. For bone tissue engineering, polymer-based composite scaffolds containing bioceramics such as hydroxyapatite can be produced and used. The bioceramics can be either incorporated in the scaffolds as a dispersed secondary phase or form a thin coating on the pore surface of polymer scaffolds. This bioceramic phase renders the scaffolds bioactive and also strengthens the scaffolds. There are a number of methods that can be used to produce bioceramic-polymer composite scaffolds. This paper gives an overview of our efforts in developing composite scaffolds for bone tissue engineering.
Authors and Affiliations
Min Wang
Keywords
Related Articles
- EP ID EP107440
- DOI -
- Views 119
- Downloads 0
Bioceramics for Tissue Engineering Applications – A Review
Three dimensional (3-D) scaffolds have been explored in an attempt to persuade the body to heal or repair tissues that do not do so spontaneously. Considerable advances in tissue engineering and regeneration have been...
Nanoceramic Matrices: Biomedical Applications
Natural bone consisted of calcium phosphate with nanometer-sized needle-like crystals of approximately 5-20 nm width by 60 nm length. Synthetic calcium phosphates and Bioglass are biocompatible and bioactive as they bo...
An Alternative to the Traditional Western Blot For Recombinant His-tagged Proteins
A rapid, inexpensive and sensitive alternative to the traditional Western Blot is presented here. This method is very useful for detection of recombinant 6-his tagged proteins.
On Application of Carhart Atom Pairs to Predict Anticonvulsant Activity
About 50 million people in the world suffer from epilepsy, especially in childhood, adolescence and old age. Available treatment fails to control epilepsy in up to 30% of affected people. In developing countries, howev...
Composite Scaffolds for Bone Tissue Engineering
Biomaterial and scaffold development underpins the advancement of tissue engineering. Traditional scaffolds based on biodegradable polymers such as poly(lactic acid) and poly(lactic acid-co- glycolic acid) are weak and...