Concentration of Calcium, Phosphate and Fluoride Ions in Microbial Plaque and Saliva after Using CPP-ACP Paste in 6-9 year-old Children
Journal Title: Journal of Dental Biomaterials - Year 2016, Vol 3, Issue 2
Abstract
Statement of Problem: Dental caries is one of the most common chronic diseases in children. The balance between demineralization and remineralization of the decayed teeth depends on the calcium and phosphate content of the tooth surface. Therefore,if a product such as casein phospho peptides - amorphous calcium phosphate (CPPACP) which can significantly increase the availability of calcium and phosphate in the plaque and saliva should have an anti-caries protective effect. Objectives:The purpose of this study was to evaluate the concentration of calcium, phosphate and fluoride in the plaque and saliva of childrenm before and after applying the CPP-ACP paste. Materials and Methods: A total of 25 children aged between 6-9 years were selected for this clinical trial study. At first, 1 ml of unstimulated saliva was collected and then 1 mg of the plaque sample was collected from the buccal surfaces of the two first primary molars on the upper jaw. In the next step, CPP-ACP paste (GC Corp, Japan) was applied on the tooth surfaces and then the plaque and saliva sampling was performed after 60 minutes. The amount of calcium ions was measured by Ion meter instrument (Metrohm Co, Swiss) and the amounts of phosphate and fluoride ions were measured by Ion Chromatography instrument (Metrohm Co, Swiss). Data were analyzed using paired t-test at a p < 0.05 level of significance. Results: There were statistically significant differences in the calcium and phosphate concentration of the saliva and plaque before and after applying the CPP-ACP paste. There were also statistically significant differences in the fluoride levels of the plaque before and after applying the CPP-ACP paste. However, there were no statistically significant differences in the fluoride levels of the saliva before and after applying the CPP-ACP paste. Conclusions: In this study, the use of the CPP-ACP paste significantly increased the fluoride levels of the plaque and the calcium and phosphate levels of both saliva and plaque. Hence, CPP-ACP paste can facilitate the remineralization of tooth surfaces and is useful for protecting the primary teeth.
Authors and Affiliations
HR Poureslami, Ra Hoseinifar, Re Hoseinifar, H Sharifi, P Poureslami
Keywords
Related Articles
- EP ID EP248759
- DOI -
- Views 75
- Downloads 0
In vitro Investigation of Hydro-alcoholic Extract of Helichrysum leucocephalum on the Inhibition of Streptococcus Mutans Growth
Statement of Problem: Indiscriminate use of antibacterial agents increases the antibiotic resistance, which consequently necessitates seeking alternatives such as herbal remedies. Objectives: The aim of this study was to...
Bioactive Glasses in Dentistry: A Review
Bioactive glasses are silicate-based and can form a strong chemical bond with the tissues. These biomaterials are highly biocompatible and can form a hydroxyapatite layer when implanted in the body or soaked in the simul...
Novel User-friendly Device for Human Bite Force Measurement
Statement of Problem: Bite force is generated due to the consonance between different parts of the masticatory system. In dentistry, measurement of the bite force is quite common through several methods and devices. Obje...
The Effect of Fracture Pattern of Anterior Teeth on Fracture Strength of Silorane- Based and Nanohybrid Composite Restorations
Statement of problem: One of the most important concerns in choosing a treatment plan for a fractured anterior teeth is their fracture pattern. Selecting the best restorative material is crucial in restoration of them....
Effect of Caries Removal Methods on the Shear Bond Strength of Resin and Glass IonomerAdhesives to Primary Dentin
Statement of Problem: There is no enough published data about the shear bond strength of resin modified glass ionomer adhesives on caries-affected primary tooth dentin excavated using minimally invasive systems. Objectiv...