Concomitant Incontinentia pigmenti and antiphospholipid antibody syndrome leading to diagnostic dilemma in a case of bad obstetric history: First report of the association
Journal Title: International Journal of Biomedical and Advance Research - Year 2017, Vol 8, Issue 10
Abstract
Antiphospholipid Antibody syndrome (APS) is an autoimmune disease characterized by recurrent thrombotic events, pregnancy morbidity, and persistence of Antiphospholipid antibodies (APLA). Incontinentia pigmenti is a rare X-linked dominant disorder, lethal in the majority of affected males in utero and variably expressed in females. Herein we present a case of a cutaneously asymptomatic lady with bad obstetric history who was detected to have APLA syndrome during Antenatal Care, with a dermatological referral to the dermatologist of her offspring leading to detection of Incontinentia pigmenti in the otherwise healthy offspring. We present this case to highlight the diagnostic difficulties in the coexistence of these two conditions in the same patient, particularly when the autosomal dominant gene is not expressed in females.
Authors and Affiliations
D P Singh, Brijesh C Nair, K G Prasad, Madhusudan Dey
Keywords
Related Articles
- EP ID EP384115
- DOI 10.7439/ijbar.v8i10.4425
- Views 87
- Downloads 0
Correlation between Glycated hemoglobin and Lipid profile in Type 2 Diabetic population of district Meerut, U.P.
Background: The Type 2 diabetes mellitus is becoming more and more prevalent in our country India and it is estimated that approximately around 2% of the Indian population i.e around 15 million peoples are suffering from...
Comparative study of Tzanakis score vs Alvarado score in the effective diagnosis of acute appendicitis
Background: Acute appendicitis is the most frequent surgical emergency encountered worldwide. Diagnostic errors are common resulting in median incidence of perforation 20% and negative appendicectomy 2% to 30%.This study...
Anti Ulcer Activity of the Ethanolic and Aqueous Extracts Of Mikania scandens in Rats
Background: Mikania scandens (family: Asteraceae), known as climbing hempvine, is a twining herb with long petioles, opposite leaves and small monogamous flower heads. It has been used in traditional medicine as an analg...
Lipid parameters in a hypofunctioning thyroid gland
Background: Hypofunctioning of the thyroid gland is associated with lipid abnormalities. There is an inverse relation between the lipid parameters and the thyroid hormones. Management of such abnormalities becomes essent...
Maternal and perinatal outcome in pregnancy with severe anaemia
Anemia is the most preventable cause of maternal and perinatal mortality and morbidity. This study was carried out to evaluate the maternal and perinatal outcome in pregnancy with severe anaemia. This hospitalized based...