Congenital Rubella Syndrome in a Term Male Neonate with Patent Ductus Arteriosus and Bilateral Nuclear Cataracts: A Case Report
Journal Title: Scholars Journal of Medical Case Reports - Year 2015, Vol 3, Issue 6
Abstract
Transplacental transmission of rubella virus leads to Congenital Rubella Syndrome. It is comprised of congenital cardiac defects (most commonly patent ductus arteriosus), cataracts and sensorineural hearing loss. While prematurity and intra uterine growth retardation are frequent accompaniments of congenital rubella syndrome, at times birth weight can be normal. The possibility of fetal anomalies due to rubella virus is highest in the first 12 weeks of gestation, which decreases thereafter. PDA is highly prevalent in premature neonates, where as its presence in term neonates signifies either intra uterine infection or genetic disease. A 39weeks, 3200grams, appropriate for gestational age, male neonate was born by vaginal delivery with normal APGARS. The neonate presented with respiratory distress, precardial activity and cardiac murmur on 4th day of life. Hence, congenital heart disease was considered and echocardiography revealed patent ductus arteriosus. While PDA is common in premature neonates, it is a rare manifestation in term newborn babies. The neonate also had bilateral nuclear cataracts in the eyes, implying congenital rubella syndrome and was investigated for the same. Other systemic findings like bilateral cryptorchidism, hepatosplenomegaly and thrombocytopenia were also evident. In addition there was unconjugated hyperbilirubinemia and elevated transaminases. There were no intra cranial calcifications in neurosonogram. Congenital rubella syndrome was confirmed as rubella IgM levels in both mother and neonate were elevated. The neonate received decongestive therapy for patent ductus arteriosus. We report a term, male appropriate for gestational age neonate with PDA and bilateral nuclear cataracts along with elevated rubella IgM levels confirming congenital rubella syndrome. Keywords: Congenital rubella syndrome, congenital cataract, congenital heart disease, neonate, Patent Ductus Arteriosus, TORCH infection.
Authors and Affiliations
Dr. S. Pratap Rao, Dr. Swathi Chacham, Dr. U. Narayan Reddy, Dr. J. Ravi kiran, Dr. Soumya anumula, Dr. Faraaz Adil, Dr. Burli Prithvi, Dr. Naila Mazhar
Keywords
Related Articles
- EP ID EP375933
- DOI -
- Views 111
- Downloads 0
Mystery of Forgotten Ear Ring
Foreign bodies in the external ear canal present frequently particularly in paediatric population. The patients introduce most foreign objects; however insects may enter into the meatus accidentally. We present a 29 year...
Mucoepidermoid carcinoma of buccal mucosa masquerading as oral fibroma
Mucoepidermoid carcinoma is a type of cancer which is found primarily in the major and minor salivary glands but they can also develop in other glands such as the tear glands, breast and thyroid. This cancerous growth de...
Anatomical Variations in relation to Anterior Group of Forearm Muscles -A Case Report
The muscles are notoriously variable and is quite common to find muscular anomalies in the course of routine dissection of human body. The anterior group of muscles are often divided into three layers i.e Superficial, In...
Pregnancy with Immune Thrombocytopenic Purpura and Neonatal Alloimmune Thrombocytopenia – Case Report
Immune thrombocytopenic purpura (ITP) is a diagnosis of exclusion. It is an autoimmune disorder caused by development of IgG autoantibodies, directed against number of platelet glycoproteins. A 28 years, primigravida, bo...
The Evolution of an Essential Thrombocythemia Diagnosed During an Ischemic Stroke
Abstract: It is unfortunate that many patients with essential thrombocythemia are diagnosed during a thrombotic event (sometimes with disabling consequences) and are not detected by regular screening actions made by fami...