Conocarpus erectus L., a plant with a high content of structural sugars, ions and phenolic compounds, shows antioxidant and antimicrobial properties promoted by different organic fractions
Journal Title: Asian Pacific Journal of Tropical Biomedicine - Year 2018, Vol 8, Issue 9
Abstract
Objective: To evaluate the structural and chemical composition of plant and the antioxidant and antimicrobial activities promoted by hexanic, ethanolic and ethyl acetate fractions obtained from leaves of Conocarpus erectus. Methods: Organic fractions were characterized through UPLC-MS and GC-MS. Antioxidant potential was performed through DPPH and molybdenum phosphate techniques. Antibacterial and antifungal assays were performed in accordance with Clinical and Laboratory Standards Institute protocols. Results: The obtained biomass of Conocarpus erectus leaves showed the high presence of glucose (0.45 g/L), cellulose (28.69%), Na (55.126 μg/L) and K (31.163 μg/L). We identified seven compounds in the hexanic and ethyl acetate fractions, and eight compounds in ethanolic fraction. Moreover, phenolic compounds are prevalent in all organic fractions with values of (10.04 ± 0.24), (221.26 ± 1.84), (340.53 ± 0.84) mg/g GAE to hexanic, ethyl acetate and ethanolic fraction, respectively. Antioxidant results showed a high potential in ethyl acetate fraction (71.82 ± 6.87)% and (10.89 ± 0.05)% in DPPH and molybdenum phosphate techniques, respectively. The ethanolic fraction showed moderate bacteriostatic and bactericidal activity against Staphylococcus aureus and presented a high fungistatic potential for all Candida species tested. Conclusions: Organic fractions obtained from leaves of Conocarpus erectus present antimicrobial and antioxidant properties, and these findings contribute to scientific information for the effectiveness on use of this plant in the development of a phytotherapic compound.
Authors and Affiliations
Dayane Kelly Dias do Nascimento Santos, Weslley Henrique de Oliveira Melo, Anastássia Mariáh Nunes de Oliveira Lima, Iranildo José da Cruz Filho, Gláucia Manoella de Souza Lima, Túlio Diego da Silva, Maiara Celine de Moura, Márcia Silva do Nascimento, Ana Maria Souto Maior, Thiago Henrique Napoleão, Cristiane Moutinho Lagos de Melo
Keywords
Related Articles
- EP ID EP405854
- DOI 10.4103/2221-1691.242292
- Views 76
- Downloads 0
Nutrition and exercise can attenuate inflammatory and psychobiological changes in hypoxia?
Exposure to hypoxia causes damage in several physiological systems, whose tissues are dependent on the O2 supply. Recently, there has been growing attention on the immunosuppressive and inflammatory potential of the hypo...
Comparison study of anti-microbial activity between crude extract of Kappaphycus alvarezii and Andrographis paniculata
Objective: To evaluate the antimicrobial properties of Kappaphycus alvarezii (K. alvarezii) and Andrographis paniculata (A. paniculata) and to compare the microbial inhibition activities between these two crude extracts....
Identification of commonly regulated genes in HPV18- and HPV16-infected cervical cancer cells treated with the curcumin analogue 1,5-bis(2-hydroxyphenyl)- 1,4-pentadiene-3-one
Objective: To identify commonly regulated genes in HPV-infected HeLa and CaSki cervical cancer cells treated with curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one (MS17) and to explore potential mechanisms...
Larvicidal efficacy of crude and fractionated extracts of Dracaena loureiri Gagnep against Aedes aegypti, Aedes albopictus, Culex quinquefasciatus, and Anopheles minimus mosquito vectors
Objective: To evaluate the larvicidal efficacy of crude and fractionated extracts of Dracaena loureiri endocarp against Aedes aegypti, Aedes albopictus, Culex quinquefasciatus, and Anopheles minimus mosquitos. Methods: L...
Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack
Objective: To examine the in vitro and in vivo anti-inflammatory effects of the alkaloid enriched extract (ELA) from the roots of Eurycoma longifolia. Methods: The in vitro antiinflammatory effects of ELA were evaluated...