Continuous Muscle Fibre Activity, Issacs’ Syndrome: A Case Report from Central India
Journal Title: Scholars Journal of Medical Case Reports - Year 2015, Vol 3, Issue 5
Abstract
Abstract: Continuous muscle fibre activity or Isaacs’ syndrome is a rare condition which represents more severe phenotype of peripheral nerve hyper excitability. It is characterized by muscle twitching, stiffness& hyperhidrosis. The diagnosis of Isaacs’ syndrome or neuromyotonia is based on clinical features & classical electromyography findings. We report a twenty six year old man complaining of continuous twitching all over his body and increased sweating. General physical & neurological examination was normal except generalized fasciculation’s & hyperhidrosis. Electromyography findings showed classical neuromyotonic & myokymic discharges. The abnormal activity was characterized by doublets, triplets or multiplet single unit discharges that have a high intraburst frequency. This patient was diagnosed as a case of Isaac’s disease & treated with tablet carbamazepine 400 mg per day. His symptoms were gradually improved. Keywords: Isaac’s syndrome, Neuromyotonia, Myokymia, Electromyography (EMG)
Authors and Affiliations
Wakode S L, Wagh S, Ramteke S G
Keywords
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