Correlation between symptoms and sign of drug users with dry eye
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 12
Abstract
AIM: To investigate the correlation between symptoms and sign of drug users with dry eye. <p>METHODS: Eighty-seven patients(87 eyes)with dry eye syndrome who were abstained from a compulsory rehabilitation center in Yangpu District of Shanghai from October 2017 to February 2018 were selected as test group. And 90 eyes of 90 patients with non-dry eye syndrome who were abstained from the same center during the same period were selected as control group. All subjects were selected for the right eye. All the patients were analyzed including dry eye questionnaire-5, ocular surface disease index(OSDI)questionnaire survey, symptoms, tear height test, break-up time test, sodium fluorescein staining test, tear osmotic pressure, Schirmer Ⅰ test and Meibomian gland function tests. Pearson and Spearman correlations were used to analyze the relationship between symptoms and signs of drug users with dry eye. <p>RESULTS: Both the DEQ-5 questionnaire and the OSDI questionnaire scores were negatively correlated with BUT values(<i>r</i>=-0.791, -0.849, <i>P</i><0.01), and were also positively correlated with corneal fluorescein sodium staining(DEQ-5: <i>r</i>=0.652, <i>P</i><0.01; OSDI: <i>r</i>=0.571, <i>P</i><0.05). The scores of DEQ-5 questionnaire and OSDI questionnaire were not significantly correlated with tear height, tear osmotic pressure, Schirmer Ⅰ test, and Meibomian gland functional score. Fatigue, dryness, and visual acuity were the three most common symptoms(69.0%, 63.2%, 55.2%, respectively). The negative correlation was shown between photophobia and tear height(<i>r</i>=-0.218, <i>P</i>=0.023). Dryness, fatigue, pain/sting, visual acuity were also negatively correlated with BUT(<i>r</i>=-0.057,-0.197, -0.053, -0.068, <i>P</i><0.05). The positive correlation was shown between dryness, fatigue, visual acuity and FL(<i>r</i>=0.169, 0.201, 0.226, <i>P</i><0.05), tearing and tear osmotic pressure(<i>r</i>=0.315, <i>P</i>=0.013), dryness and Schiemer Ⅰ(<i>r</i>=0.324, <i>P</i>=0.043). Visual acuity was positively correlated with meibomian gland function(<i>r</i>=0.227, <i>P</i>=0.011). The difference in tear height, corneal fluorescein sodium staining, and tear osmotic pressure were statistically significant between dry eye patients and normal group(<i>P</i><0.05). The differences in BUT, Schirmer Ⅰ test and meibomian gland function were not statistically significant(<i>P</i>>0.05). <p>CONCLUSION: The clinical symptoms of dry eye in drug users are not obvious, and their correlation with the test results is poor. Clinicians should pay attention to the medical history inquiry, physical examination, and the refinement and individualization of diagnosis.
Authors and Affiliations
Jian-Qun Ha
Keywords
Related Articles
- EP ID EP501609
- DOI 10.3980/j.issn.1672-5123.2018.12.22
- Views 131
- Downloads 0
Effectiveness and prognosis of 23G vitrectomy for perforating ocular trauma caused by metallic foreign bodies
AIM: To summarize the characteristics of ocular perforation caused by metallic foreign body, evaluate the effectiveness and safety of 23G vitrectomy, and analyze the factors that affect the final vision of patients with...
Effects of FOXO4 on oxidative stress and apoptosis of retinal vascular endothelial cells under high glucose environmental conditions
AIM: To study the effects of FOXO4 on oxidative stress and apoptosis of retinal vascular endothelial cells under high glucose environmental conditions. <p>METHODS: Human retinal vascular endothelial cells were cultured w...
Changes and effects of orthokeratology on cornea morphology
AIM:To investigate the changes and effects of orthokeratology on corneal morphology. <p>METHODS: Totally 90 patients were treated with orthokeratology from January 2015 to December 2016. They were divided into observatio...
Analysis on screening results of 2 203 premature infants with retinopathy
AIM: To investigate the incidence and risk factors of retinopathy of prematurity(ROP)in preterm infants. <p>METHODS: The wide-field digital pediatric Retinal imaging system was used to screen 2 203 preterm infants with g...
Research progress on anti-scarring drugs after glaucoma filtration surgery
Glaucoma filtration surgery is currently the preferred method for patients in whom anti-glaucoma medication and laser treatment can not control intraocular pressure, and its postoperative filtering bleb scar formation is...