Correlation of 24-hour urinary protein, urinary protein: Creatinine ratio and HBA1c in type 2 diabetes with and without nephropathy
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 3, Issue 2
Abstract
Background: The leading cause of morbidity and premature mortality in diabetics is nephropathy. closely associated with renal involvement in diabetes. Objectives: To estimate serum levels of HbA1c, 24 ratio in Type 2 diabetics with and without nephropathy. urinary protein and HbA1c levels in these groups. department of Biochemistry, Owaisi Hospital, from October 2016 to May 2017 on 103 diabetes patients comprising of 41 diabetics without ephropathy (Group A) and 62 Type 2 diabetes subjects with nephropathy (Group B) parameters were estimated: Fasting blood glucose, Serum creatinine, HbA1c Results show that the mean values of fasting blood protein to creatinine ratio are significantly increased in Group B when compared to Group A and these parameters are further increased in diabetic subjects with P: C ratio protein: creatinine ratio levels are significantly increased (p< 0.001) with proteinuria more than the physiological range (P: C ratio 0.2) than within physiologicalrange (P: C < positively with high gnificance.HbA1c levels correlated positively with both P:C ratio and 24 levels. Conclusion: This study suggests estimating HbA1c as an indicator of gl method for early diagnosis and intervention for diabetic nephropathy.
Authors and Affiliations
S Mohammed, F Nazki
Keywords
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