Correlation of 30 consecutive idiopathic pulmonary fibrosis patients intertiary care center
Journal Title: Journal of Medical and Scientific Research - Year 2015, Vol 3, Issue 4
Abstract
Background: Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, primarily occurring in older adults, limited to the lungs, and associated with histological and/ or radiologic pattern of usual interstitial pneumonia. The objective of the study is to correlate severity of IPF and duration of symptoms with spirometry test/ forced vital capacity (FVC), high resolution computed tomography (HRCT) findings, smoking history, age and sex of 30 consecutive IPF patients in a tertiary care centre. Methodology: The study was done on 30 consecutive patients of IPF, clinically and radiologically fulfilling the criteria for IPF. Results: The study group showed significant male predominance of 80%. Subpleural, basal predominance, reticulations and honey-combing pattern on HRCT was seen in 100%, while traction bronchiectasis in 76.7% and minimal ground glassing in 33.3%. 23 out of 30 patients presented with symptom duration of 13-18 months, with mean duration of 16.4 months. 53.3% of the study population were smokers, 26.6% ex-smokers. Conclusion: Clinicians should integrate clinical, radiological and/ or pathological data to support the diagnosis of IPF. Smokers are at particular risk for IPF and should be watched for at every visit. As IPF evolves over a period of time, early CT chest may not have all the radiological features supporting IPF. Close follow up is therefore suggested.
Authors and Affiliations
Qureshi A, Latha S, Vijayalakshmi A, Nandan P, Mohit C
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