Correlation of carotid intima media thickness with SGOT in diabetic patients–An analytical cross-sectional study in a tertiary care hospital
Journal Title: BOHR International Journal of Current Research in Diabetes and Preventive Medicine - Year 2024, Vol 2, Issue 1
Abstract
Background:Uncontrolled diabetes mellitus predisposes to atherosclerotic cardiovascular diseases like coronaryartery disease, Stroke leading to illness, complications, and death. Carotid intima media thickness (CIMT),performed by radiologists being simple and noninvasive, has been regarded as a tool to diagnose earlyatherosclerosis. Aspartate aminotransferase (AST) is a cardiac biomarker whose level will be elevated in myocardialinjury and inflammation. This study was conducted to find correlation of SGOT with CIMT in diabetes patients. Methods:29 patients with type 2 diabetes mellitus were selected for this hospital-based analytical cross-sectionalstudy. SGOT and CIMT were measured. The correlation between SGOT and CIMT was analyzed using Pearsoncorrelation analysis. Results:Of the 29 patients enrolled 34.5 % were female and 65.5 % were male. A statistically significant correlationwas found between HbA1C, FBS with CIMT (p<0.001). The mean age was 66.32±10.981. 55% of the patientshad CIMT more than 0.9 mm. We found a statistically significant correlation between SGOT and CIMTr= 0.415with ap-value of 0.025. Conclusion:SGOT is having a positive correlation with CIMT in diabetic patients. Hence SGOT can be utilizedas a marker to prognosticate early atherosclerotic cardiovascular events like stroke and ischemic heart disease indiabetic individuals.
Authors and Affiliations
Sumesh Raj Sree Rekha Sreekumaran Retnamma Santheev Sasidharan
Keywords
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- EP ID EP744709
- DOI 10.54646/bijrdpm.2024.11
- Views 32
- Downloads 0
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