Correlation of Forced Expiratory Time with Anthropometric and Spirometric Indices
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 1
Abstract
ABSTRACT Introduction: Forced Expiratory Time (FET) is the duration of forceful expiration during a Forced Vital Capacity (FVC) manoeuver of spirometry test. Joint recommendation of the American Thoracic Society (ATS) and the European Respiratory Society (ERS) i.e., ATS/ERS has expressed new interest about FET in their latest guidelines (2005). Interpretation of FET in respect to anthropometric and spirometric determinants in the population of eastern India is yet to be established. Aim: To evaluate the correlation of FET with anthropometric {age and Body Mass Index (BMI)} and spirometric indices (FEV1/FVC ratio and PEFR) in subjects having normal range of commonly used spirometry parameters such as FVC, Forced Expiratory Volume in first second (FEV1), FEV1/FVC ratio, forced expiratory flow in the middle half of the FVC (FEF25%-75%), and Peak Expiratory Flow Rate (PEFR). Materials and Methods: A retrospective study was conducted based on spirometry results obtained between February 2016 and July 2016 from the saved database at pulmonary function laboratory of Department of Physiology, RG Kar Medical College, Kolkata, West Bengal, India, after obtaining administrative approval. A total of 220 non-smoker subjects aged between 25 and 50-years including male and female (1:1) having normal spirometry were selected for analysis where the test was conducted by HELIOS 702 as per ATS/ERS protocol (2005) and using 80% ethnic correction during that time period. Age, Sex, BMI, FEV1/FVC ratio (ratio between forced expiratory volume in first second and forced vital capacity), PEFR (percentage value) and FET (seconds) were collected from the record sheet of each patients. Statistical analysis was done by chi-square test, two-sided z-test and Pearson’s correlation coefficient. Differences were found statistically significant at p-value <0.05. Results: In the present study both age and BMI had shown significant positive correlation {(r:+0.445; p<0.001) and (r:+0.239; p=0.002) respectively} while both FEV1/FVC ratio and PEFRwere presented significant negative correlation {(r:−0.639; p<0.0001) and (r:−0.285; p<0.0001)} with FET. Conclusion: FET increases with age suggesting age related alteration in pulmonary mechanics and positive correlation with BMI denotes FET as an indicator of pulmonary efficiency in obese. Negative correlation of FET with FEV1/FVC and PEFR may suggest airflow limitation and indicates that FET has a diagnostic value in obstructive airway diseases.
Authors and Affiliations
Sujoy Mukherjee, Anil Baran Singha Mahapatra
Keywords
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- EP ID EP555070
- DOI 10.7860/JCDR/2019/38007.12469
- Views 97
- Downloads 0
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