CORRELATION OF PORTAL VEIN DIAMETER, SPLENOMEGALY AND THROMBOCYTOPAENIA WITH GASTRO-OESOPHAGEAL VARICES IN CIRRHOTIC PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 83
Abstract
BACKGROUND The word cirrhosis comes from the Greek word kirrhos, which means orange yellow.1 Cirrhosis is a chronic disease of the liver in which diffuse destruction and regeneration of hepatic parenchymal cells and diffuse increase in connective tissue has resulted in disorganisation of the lobular architecture, which leads to various complications such as portal hypertension and its sequelae including gastro-oesophageal varices and splenomegaly, thrombocytopaenia, etc. The aim of this study is to study the correlation of portal vein diameter, splenomegaly and thrombocytopaenia with gastrooesophageal varices in cirrhotic patients. MATERIALS AND METHODS This is an observational study including 100 patients of cirrhosis attending OPD/ admitted in various wards of Guru Nanak Dev Hospital and allied group of hospitals attached to Government Medical College, Amritsar. RESULTS Most of the patients in our study had grade II oesophageal varices (29%) and the most common age distribution in patients with grade II varices is 25 - 75 years. In our study, it is seen that portal vein diameter increases with development of gastro-oesophageal varices (p-value < 0.001). Spleen size increases with formation of gastro-oesophageal varices (p-value < 0.001). Platelet count decreases with the development of gastro-oesophageal varices (p-value < 0.001). CONCLUSION It is concluded from our study that there is a positive correlation between portal vein diameter and splenomegaly with gastrooesophageal varices and an inverse relationship between thrombocytopaenia and gastro-oesophageal varices.
Authors and Affiliations
Krishan Oberoi, Upasana Upasana
Keywords
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- EP ID EP276111
- DOI 10.14260/jemds/2017/1260
- Views 73
- Downloads 0
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