Correlation of Ultrasound & Mammography to Histopathology Results in Breast Cancer. A One Year Study at King Khalid Hospital, Najran, Saudi Arabia
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 71, Issue 2
Abstract
<strong>Objective</strong>: To compare the ultrasound & mammography results to histopathology reports of breast cancer cases presented in King Khalid hospital, Najran, Saudi Arabia, 2016. <strong> Methods:</strong>This retrospective cross-sectional analytic study was performed on 105 patients with breast lumps, who were referred to breast clinic King Khalid hospital Najran, during 2016. The patients’ information was recorded using a checklist, which included name, code, age, ultrasonography, and mammography results and pathology reports. The results of ultrasonography and mammography were compared with histopathology. The results were analyzed on SPSS (version 16). <strong>Results: </strong>The mean age of the patients was 42.3 (±5) years. Our results showed that in histopathology reports, in (30/105) patients i.e. 28.6% were malignant, 26 patients (24.8%) biopsy revealed benign disease. Examination with mammogram revealed that, 33/105 i.e. (31.4%) were malignant and 40 cases (38.1%) had benign disease. On ultrasound examination, 21/105 (20%) were malignant and 43(40.1%) had benign disease.The mammography sensitivity was 76.6% and ultrasound sensitivity was 60%<strong>. </strong>Breast Imaging-Reporting and Data System (BIRADS) by mammogram revealed the categories as follows; category 0 in 21.9%, 2in 11.4%, 3 in 31.4, 4 in 5.7%), 4a in 6.7%, 4b in 4.8%, 4c in1.9%, 5 in 8.6% in 6 in 4.8% and unclear in 2.9% of cases.Retro areolar area was involved in 24.8%, Upper Outer Quadrant in 45.7%, Upper Inner Quadrant in 3.8%, Lower Outer Quadrant in 4.8%, Lower Inner Quadrant in 8.6%, Diffuse involvement in 9.5% and unable to pick in 2.9%. By mammogram, the calcification found revealed 15.2% of examined patients had malignant lesions. Findings of lymph nodes examination by mammogram revealed 5.7% of the examined patients had malignant lesions. Significant difference (P<0.05) regarding the age group was found in pathology and mammogram results.<strong> Conclusion: </strong>This study showed that mammography is the preferred diagnostic tool in screening early breast cancer patients aged above than 40 years with a higher sensitivity; the results are near to open biopsy. For the younger age group the use of ultrasonography in cases with high breast density is promising.
Authors and Affiliations
Eman Helal
Keywords
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