Correlations between Fasting Salivary Glucose and Fasting Plasma Glucose in Type 2 Diabetes Mellitus
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Background : Early detection & screening of type 2 Diabetes Mellitus (DM) is essential to delay its complications. However, testing for DM often requires invasive and painful blood testing which deters the people from undergoing an investigation and they remain undetected for a very long time. So, there is a need for non-invasive testing. Aim : This study aimed at estimating and correlating fasting salivary glucose and fasting plasma glucose in type 2 diabetics and non-diabetics; so as to assess if salivary glucose can be used as a non-invasive tool, to evaluate blood glucose levels, and could it also be used as a biomarker for large scale screening of diabetes. Method : 50 type 2 diabetic and 50 non-diabetic participants were selected according to inclusion & exclusion criteria. Quantitative estimation of blood and salivary glucose were performed by glucose oxidase method. Pearson’s correlation coefficient test was applied to assess the correlation between salivary glucose level and plasma glucose level. Result : The mean salivary glucose was significantly greater in type 2 diabetics (1.45 ± 0.91 mg/dL) as compared to non-diabetic participants (0.41 ± 0.29 mg/dL). A positive, significant but moderate correlation was seen in both type-2 DM patients (r = 0.43; p = 0.002) and in non-diabetics (r = 0.44; p = 0.001). The sensitivity and specificity were 66% and 96% at 1mg/dl respectively. Conclusion : Fasting salivary glucose could potentially be used as a non-invasive tool for monitoring and for large scale screening of type 2 DM.
Authors and Affiliations
Dr. Beulah Rainer, Dr. Pratibha Deshmukh
Keywords
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- EP ID EP377305
- DOI 10.9790/0853-1707054044.
- Views 75
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