Cost Analysis of Ertapenem Therapy for Urinary Tract Infections and Assessment of Its Suitability for Outpatient Parenteral Antibiotic Therapy Programme in Turkey

Abstract

Introduction: The primary aim of this study was to evaluate whether there was a difference between outpatient parenteral antibiotic therapy (OPAT) and inpatient parenteral antibiotic therapy (IPAT) costs of ertapenem for urinary tract infections (UTI’s) due to extended-spectrum beta-lactamase (ESBL)-producing Gram-negative bacilli, and to discuss suitability of ertapenem for OPAT programme of Turkey for the near future. Materials and Methods: A total of 53 patients hospitalized with the diagnosis of UTI and treated with ertapenem were retrospectively evaluated. The cost of ertapenem treatment as IPAT was actual costs retrieved from the hospital records. The estimated cost of the same antibiotic for the same patients as an OPAT programme was then calculated and the costs were compared. Results: The cost difference between IPAT and OPAT was ₺ 12.305 (€ 5783). Outpatient parenteral antibiotic therapy programme would provide an estimated 20% reduction in treatment costs. The estimated number of bed days saved, if the patients had received the treatment as OPAT, was calculated to be 583 days, which constitutes about 5% of the total number of hospitalization days. Conclusion: Applying ertapenem therapy through OPAT programme for UTIs caused by ESBL-producing Gram-negative bacilli will decrease the financial burden of health expenditures and the number of inpatient bed days in Turkey.

Authors and Affiliations

Bahar ÖRMEN, Nesrin TÜRKER, Nurbanu SEZAK, Zerrin KARA, Figen KAPTAN, Tuna DEMİRDAL, Melih Kaan SÖZMEN

Keywords

Related Articles

New Antibiotics in the Therapy of Osteomyelitis

Osteomyelitis is probably the oldest known infection in the history of life. It can develop secondary to local tissue disruption, ischemia and associated chronic wounds or via hematogenous infection. Although it has been...

Herd Immunity and Measles

The term “herd immunity” is an immunization concept that refers to a means of protecting a whole population from an infectious disease by immunizing a certain percent of a population. Measles is a highly contagious infec...

Problems in Infectious Diseases and Clinical Microbiology Residency Training

Introduction: In this study, it was aimed to determine the problems encountered by Infectious Diseases and Clinical Microbiology residents during residency training in order to identify solutions to these difficulties....

Hemophilia Patients’ Level of Knowledge of About Viral Hepatitis

Introduction: Hemophilia is a genetic disease presenting predominantly with joint hemorrhages in clinical course. Thus, its treatment requires transfusion of numerous blood and blood products. As a consequence, hemophili...

Download PDF file
  • EP ID EP689352
  • DOI 10.4274/mjima.2017.7
  • Views 140
  • Downloads 0

How To Cite

Bahar ÖRMEN, Nesrin TÜRKER, Nurbanu SEZAK, Zerrin KARA, Figen KAPTAN, Tuna DEMİRDAL, Melih Kaan SÖZMEN (2017). Cost Analysis of Ertapenem Therapy for Urinary Tract Infections and Assessment of Its Suitability for Outpatient Parenteral Antibiotic Therapy Programme in Turkey. Mediterranean Journal of Infection, Microbes and Antimicrobials, 6(1), -. https://www.europub.co.uk/articles/-A-689352