Crystallography and Biopharmaceutics of Some Antimalarials
Journal Title: Journal of Pharmaceutical Research International - Year 2015, Vol 5, Issue 6
Abstract
Crystallography is a branch of science that deals with the discerning of the arrangement and bonding of atoms in crystalline solids. Crystal structural differences in the active pharmaceutical ingredient (API)/excipients in multi-source generics of antimalarials may present differences in their physicochemical properties and ultimately the rate and extent of drug absorption. Tackling the menace of the continuing spread of multi-drug resistant Plasmodium falciparum malaria may require the evaluation of the crystal structural influences of orally administered drugs on antimalarial bioavailability.
Authors and Affiliations
Sunday O. Awofisayo, Augustine O. Okhamafe, Ehijie F. O. Enato, Matthew I. Arhewoh
Keywords
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- EP ID EP344425
- DOI 10.9734/BJPR/2015/15832
- Views 97
- Downloads 0
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