CURRENT STATUS OF EPILEPSY IN MALAYSIA AND WAY AHEAD
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 1
Abstract
Epilepsy is the third most common neurological disorder, following stroke and Alzheimer’s disease with the highest frequency of newly identified cases occurring among children and adults. About 50 million people worldwide have epilepsy, and nearly 80% of epilepsy occur in developing countries including Malaysia. In Malaysia, epilepsy is still a highly misunderstood and a number of studies explored the poor understanding of the illness. Epilepsy patients have the serious impact on quality of life. Both individuals and families of the patients have an appalling experience. Another factor is cost of AEDs which is very high. It is a burden for both patients and their families to meet the costs. There is a significant need persists to develop an accessible, cost effective, efficacious and less toxic antiepileptic drugs. Natural products used in traditional herbal medicine can be an important source for the search of novel anti-epileptogenic compounds. A number of plants used in traditional medicine have shown to possess anticonvulsant activity. Malaysia is rich in medicinal plants. Attempts have been made in the past to explore the effectiveness of some medicinal plants for the treatment of epilepsy, but the rationale for selection of plants was not justifiable and hence they failed to get a hit. Some of the Malaysian plants are used by traditional healers in the treatment of epilepsy, but their therapeutic effectiveness is not being scientifically explored. This review focused to enlighten the status of epilepsy and research required for the Malaysian medicinal plants for the treatment of epilepsy.Â
Authors and Affiliations
Alina Arulsamy, Bey Hing Goh, Mohd Farooq Shaikh
ANTIBACTERIAL ACTIVITY OF ISOLATED ENDOPHYTIC FUNGI FROM RAUVOLFIA SERPENTINA (L.) BENTH. EX KURZ
Objective: The aim of the present study was to isolate the endophytic fungi from medicinal plant Rauvolfia serpentina (L.) Benth. ex Kurz. (Family Apocynaceae) and observed their antibacterial activity against bacteria a...
LIPID LOWERING ACTIVITY OF FERONIA LIMONIA LEAF IN TRITON WR-1339 (TYLOXAPOL) INDUCED HYPERLIPIDEMIC RATS
Objectives: The present study was undertaken to assess the lipid lowering activity of methanolic extract from Feronia limonia leaf in Triton WR-1339 induced hyperlipidemic rats. Methods: Hyperlipidemia was induced in rat...
KINETIC SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF GENTAMICIN IN PHARMACEUTICAL FORMS
Objective: The objective of this study is to develop and validate new selective kinetic methods for the determination of Gentamicin in pure and pharmaceutical preparations.Methods: The proposed methods (A and B) are base...
ANTI-INFLAMMATORY ACTIVITIES OF FRUIT AND LEAVES EXTRACT OF LANNEA MICROCARPA ENGLAND K. KRAUS (ANACARDIACEAE)
Objective:Â To investigate the anti-inflammatory activity as well as carotenoid content of crude hydro-acetonic extract of fruit and leaves of Lannea microcarpa (L. microcarpa) and to elucidate the possible anti-inflamm...
PREVALENCE OF MALARIA CASES IN TEA GARDEN AREAS OF LAKHIMPUR DISTRICT, ASSAM
Objective: After observing the increasing trend in numbers of fever cases from Joyhing and Koilamari tea estate, mass fever surveys were conducted to determine the prevalence of malaria cases in the affected areas.Method...