Cytologic analysis of body fluids with an emphasis on malignant effusions
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 1
Abstract
Introduction Fluid cytology a relatively non invasive technique throws light on both malignant and non malignant causes of effusions It especially contributes in cancer research and staging of various tumorsMaterials and Methods This was a retrospective study done over a period of two years from January 2014 to December 2015 in the department of Pathology Kamineni Academy of Medical Sciences and Research Centre Hyderabad The body fluids included in the study were pleural peritoneal pericardial and synovial fluids All other fluids were excluded The relevant clinical data was noted Gross cell count and cytomorphological examinations of fluid were doneResults Out of 302 cases pleural fluids 148 490 cases were most common followed by peritoneal fluid 125 4139 cases and least common was pericardial fluid 8 264 cases The maximum numbers of cases was in 5th decade The age range was 3 years to 84 years Female preponderance was observed with M F ratio of 1 117 Lymphocyte rich exudates were most common in pleural effusion In peritoneal and pericardial effusions transudates were more and suppurative inflammation was predominant in synovial fluid analysis Over all malignant effusions constituted 1854 of effusions Metastatic adenocarcinoma was the commonest malignancy detected in all body cavity effusionsConclusions Fluid cytology is relatively painless simple cost effective rapid technique that yields quick and reliable results Some cases may present major interpretative challenges to the pathologist Ancillary studies such as cell count biochemical microbiologic evaluation cell block and immunohistochemistry IHC study help in accurate identification of diagnosisKeywords Body fluids Malignant effusions Transudates
Authors and Affiliations
Ayyagari Sudha, Padmaja Korti, Shailaja Prabhala, Ashok Kumar Deshpande
Keywords
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- EP ID EP473193
- DOI 10.18231/2394-6792.2018.0019
- Views 56
- Downloads 0
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