Cytotoxic Effect of Snake (Echis Carinatus) Venom on Human Embryonic Kidney Cells (HEK 293)
Journal Title: Clinical Medical Reviews and Case Reports - Year 2016, Vol 3, Issue 9
Abstract
The venom of snake (Echis carinatus) induces hemorrhage and necrosis locally at the bite site as well as acute renal failure (ARF) as a consequence of morphological and functional alterations in glomerular and tubular cells. Objectives: It is not clear that ARF results from a direct cytotoxic effect on renal epithelia or from a renal ischemia due to systemic hemodynamic disturbances. This work investigated the in vitro effect of Echis Carinatus crude venom, using cultured Human embryonic kidney (HEK 293) mono layers as a model to see the cytotoxic effect of Echis carinatus venom.
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- EP ID EP272173
- DOI 10.23937/2378-3656/1410132
- Views 125
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