Dapagliflozin- Induced Severe Ketoacidosis Requiring Hemodialysis
Journal Title: Clinical Medical Reviews and Case Reports - Year 2016, Vol 3, Issue 12
Abstract
The availability of novel classes of medication for the treatment of type 2 Diabetes mellitus (type 2 DM) provides doctors with options to choose individualized treatments based on patient and agent characteristics beyond metformin therapy, as per current guidelines. Independent of impaired beta-cell function and insulin resistance, sodium glucose cotransporter type 2 (SGLT2) inhibitors represent a different treatment strategy for reducing plasma glucose levels and glycosylated hemoglobin concentrations by increasing urinary glucose excretion through reduced renal glucose reabsorption.
A Case of Pyonephrosis of an Obstructed Atrophic Kidney
This case is of a 67-year-old male who presented to the office with multiple symptoms and was treated for a variety of infections before the correct diagnosis of pyonephrosis in the setting of chronic ureteropelvic junct...
Sequential, Multimodal Treatment of a Refractory Adult-Onset Still’s Disease Complicated by Reactive Hemophagocytic Lymphohistiocytosis
We report the case of a patient with severe adult-onset Still's disease not responding to treatment with high-dose corticosteroids and intravenous immunoglobulins. Partial remission was obtained under therapy associating...
Non-operative Treatment for Extensive Skin Necrosis of a Neonatal Dorsal Foot caused by Extravasation
We herein describe two cases of non-surgical treatment for skin necrosis of the dorsum of the neonatal foot caused by extravasation. In both the cases, closure of the defects was achieved after 3 months of conservative t...
A Case of Macrovascular Complications after Treatment with DPP-4 Inhibitor, Sitagliptin, in a Patient with Type 2 Diabetes Mellitus
Our case involved a 72-year-old woman [height, 1.47 m; body mass index (BMI), 19.9 kg/m2] with T2DM and cardiovascular disturbance. She had been diagnosed with non-obese T2DM (BMI, 20 kg/m2; anti-GAD antibody, negative)...
Endometrioma Complicated by a Rare Bleeding Disorder Mimicking Ovarian Cancer
Hemophilia A is a congenital X-linked recessive bleeding disorder due to factor VIII deficiency. It is exceedingly rare in females. The association of the most common bleeding disorder (Von Willebrand Disease) and hemope...