Depression and quality of life in patients with severe chronic obstructive pulmonary disease - A cross sectional study
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 4
Abstract
Background: We assessed the prevalence of depression and quality of life and their associations in patients with severe and very severe COPD. Materials and methods: Sixty individuals who gave consent and who met the gold criteria for severe and very severe COPD were recruited for the study. The results of spirometry (FEV1%) which gives the severity of COPD were noted. The recruited individuals were screened for depression through a clinical interview and ICD-10 criterion was used to diagnose depression. The severity of depression of each individual participating in the study was estimated using Hamilton Depression Rating and the quality of life of each individual was estimated using the WHO Quality of Life Questionnaire –BREF Version. Results: Mean age of the patients was 53±4.5 years. The duration of COPD was 8.68±4.3 years. 93.3% of the individuals recruited for the study had severe COPD. 68.3% had been mild to severe depression while 31.7% were normal. The mean HAM-D and quality of life total score of these patients were 17±9.09 and 52±15.1 respectively. HAM-D scores in patients suffering from very severe COPD were much higher when compared to that of patients suffering with severe COPD. Patients with severe depression have poor quality of life on all aspects in comparison with moderate and mildly depressed. Numbers of exacerbations and hospitalizations have a significant correlation with severity of depression and a significant negative correlation with all domains of quality of life. Conclusion: The prevalence of depression in patients with severe to very severe COPD is as high as 68.3%. There was a positive correlation between the number of hospitalizations and exacerbations to the severity of depression. Quality of life in COPD patients with depression was found to be poor in all the four domains namely physical, psychological, social and environmental when compared to those having only COPD as an illness. The severity of COPD was positively correlated with severity of depression and showed a negative correlation with the quality of life.
Authors and Affiliations
Lakshmi Rajesh Channareddy, Eshwar Reddy Ravula, GP Vignan Kumar
Keywords
Related Articles
- EP ID EP419881
- DOI -
- Views 114
- Downloads 0
Role of 2-D echocardiography in detecting cardiovascular abnormalities in chronic kidney disease patients: Case series of 50 chronic kidney disease patients
Background: Chronic kidney disease is a major public health problem worldwide with continuously increasing incidence and prevalence. Diabetes and hypertension are the leading causes of chronic kidney disease worldwide, w...
Perceptions of first year dental students on case based learning in Physiology
Background: Application of basic science knowledge to clinical practice is the aim of first year undergraduate dental curriculum. To bring in application of basic science theory to the clinical dental application, a case...
A study of cardiovascular manifestation in patient with hypothyroidism
Background: Reduced production of thyroid hormone is the central feature of the clinical state termed Hypothyroidism. Hypothyroidism is associated with bradycardia, a decreased cardiac output, increased vascular resistan...
Epidemiology of Parkinson's disease in South central India - A longitudinal cohort study
Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, commonly found in males above the age of 60. Increased life expectancy due to better health care and aging population will see a...
Perception of dental undergraduates and interns on radiation protection safety protocol - A questionnaire based cross-sectional study
Background: Radiographs are an important diagnostic tool for dental professionals. X-rays have the ability to penetrate human tissues. Nowadays, it is mandatory to follow ALARA principle “As Low As Reasonably Achievable”...