Detection of primary CMV infection in Sudanese pregnant women by IgG avidity test
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2016, Vol 6, Issue 10
Abstract
Objective: To diagnose primary cytomegalovirus (CMV) infection in pregnant women by determining CMV immunoglobulin G (IgG) avidity index. Methods: Ninety pregnant women with an average age of 23 years were studied. Their demographic data were obtained along with blood samples. The anti-CMV immunoglobulin M (IgM) antibodies were determined on fully automated immuoanalyzer, while the CMV IgG avidity testing was carried out using avidity ELISA assay. Results: Among the pregnant women, 15.6% were in the first trimester, 30.0% in the second, and 54.4% in the third trimesters. Besides, 40.0% had chronic disease, while the other 60.0% did not. Anti-CMV IgM antibodies and CMV IgG avidity test showed that 1.1% of the pregnant women were CMV IgM positive and 98.9% were CMV IgG positive, respectively. The avidity test revealed the presence of low avidity of CMV IgG antibodies in 1.1% cases while 98.9% cases exhibited high avidity of CMV IgG antibodies. Conclusions: CMV IgG avidity test was important to distinguish between CMV recent and past infection rather than relying on IgG and IgM only, and IgM is not always indicative for recent or primary CMV infection.
Sero-prevalence of Toxoplasma gondii infection in backyard poultry birds of Tarai Zone of West Bengal, India
Objective: To investigate the sero-prevalence of Toxoplasma gondii (T. gondii) infection in backyard poultry birds in three blocks of Tarai Zone of West Bengal during the period from January to June, 2015. Methods: A tot...
Determination of total phenolics, flvonoids and antioxidant activity of root crude extracts of Adenium obesum traditionally used for the treatment of bone dislocations and rheumatism
Objective: To prepare different polarities crude extracts from the roots of Adenium obesum (AO) and to evaluate their total phenolics, total flavonoids and antioxidant activity by FolinCiocalteu reagent, aluminum chlorid...
New emerging H5N8 inflenza: A new risk for human?
The new emerging influenza is usually important problem in medicine. There are many new emerging influenza infections that exist at present. One of the new influenza is the H5N8 influenza. This new disease has just been...
Fast track method for the identification of multi-drug resistant tuberculosis on direct clinical specimen using combined drug media
Objective: To combine isoniazid (INH) and rifampicin (RIF) in a single media to detect and evaluate multi-drug resistant Mycobacterium tuberculosis (MDR-TB) strains using clinical specimens by direct and indirect drug su...
An In vitro studies on indigenous ayurvedic plants, having hypoglycemic activity
Objective: Finding a cure for diseases and infections using herbal medicines are as old as mankind. The present study aimed at investigation of anti-hyperglycemic potential of methanolic extract of some indigenous ayurve...