Detection of primary CMV infection in Sudanese pregnant women by IgG avidity test
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2016, Vol 6, Issue 10
Abstract
Objective: To diagnose primary cytomegalovirus (CMV) infection in pregnant women by determining CMV immunoglobulin G (IgG) avidity index. Methods: Ninety pregnant women with an average age of 23 years were studied. Their demographic data were obtained along with blood samples. The anti-CMV immunoglobulin M (IgM) antibodies were determined on fully automated immuoanalyzer, while the CMV IgG avidity testing was carried out using avidity ELISA assay. Results: Among the pregnant women, 15.6% were in the first trimester, 30.0% in the second, and 54.4% in the third trimesters. Besides, 40.0% had chronic disease, while the other 60.0% did not. Anti-CMV IgM antibodies and CMV IgG avidity test showed that 1.1% of the pregnant women were CMV IgM positive and 98.9% were CMV IgG positive, respectively. The avidity test revealed the presence of low avidity of CMV IgG antibodies in 1.1% cases while 98.9% cases exhibited high avidity of CMV IgG antibodies. Conclusions: CMV IgG avidity test was important to distinguish between CMV recent and past infection rather than relying on IgG and IgM only, and IgM is not always indicative for recent or primary CMV infection.
Nontyphoidal salmonellosis and multiple ring enhancing lesions in the brain of an HIV infected adult: a diagnostic dilemma
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Antagonistic activity ofEleutherine palmifolia Linn
Objective: The aim of the present study was to investigate the phytochemical constituent and the in vitro Antimicrobial activity of the wonderful medicinal herb Eleutherine palmifolia. Methods: Eleutherine palmifolia bul...
Macroscopial, anatomical and physico-chemical studies on fruits of Coccinia indica Wight &Arn. (Cucurbitaceae)
Objective: To rationalize the macroscopial, anatomical and physico-chemical studies on fruits of Coccinia indica Wight & Arn. (Cucurbitaceae). Methods: The crude ethanolic extract of fruits of Coccinia indica Wight & Arn...
Measles and respiratory failure: Case report and review of the last European outbreaks
Measles is an preventable acute viral illness, with the potential for severe and fatal complications. According to the European Centre for Disease Prevention and Control in the last surveillance report, a total of 10 271...
Anti-nociceptive, anti-inflmmatory and anti-pyretic activities of latex and leaves methanol extract of Euphorbia helioscopia
Objective: To evaluate anti-nociceptive, anti-inflammatory and anti-pyretic activities of latex and leaves methanol extract of Euphorbia helioscopia against chemical (acetic acid induced writhing and formalin tests) and...