Detection of primary CMV infection in Sudanese pregnant women by IgG avidity test
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2016, Vol 6, Issue 10
Abstract
Objective: To diagnose primary cytomegalovirus (CMV) infection in pregnant women by determining CMV immunoglobulin G (IgG) avidity index. Methods: Ninety pregnant women with an average age of 23 years were studied. Their demographic data were obtained along with blood samples. The anti-CMV immunoglobulin M (IgM) antibodies were determined on fully automated immuoanalyzer, while the CMV IgG avidity testing was carried out using avidity ELISA assay. Results: Among the pregnant women, 15.6% were in the first trimester, 30.0% in the second, and 54.4% in the third trimesters. Besides, 40.0% had chronic disease, while the other 60.0% did not. Anti-CMV IgM antibodies and CMV IgG avidity test showed that 1.1% of the pregnant women were CMV IgM positive and 98.9% were CMV IgG positive, respectively. The avidity test revealed the presence of low avidity of CMV IgG antibodies in 1.1% cases while 98.9% cases exhibited high avidity of CMV IgG antibodies. Conclusions: CMV IgG avidity test was important to distinguish between CMV recent and past infection rather than relying on IgG and IgM only, and IgM is not always indicative for recent or primary CMV infection.
Malaria in asymptomatic migrant workers and symptomatic patients in Thamaka District, Kanchanaburi Province, Thailand
Objective: To investigate malaria infections in asymptomatic legal migrant workers and symptomatic patients in Thamaka, Kanchanaburi Province. Methods: This study was conducted during April 26-29, 2008 using thick and th...
Efficiency of Tribulus terrestris L. as an antibiotic growth promoter substitute on performance and immune responses in broiler chicks
Objective: To evaluate the effect of Tribulus terrestris L. (puncture vine) as an antibiotic growth promoter substitute on growth performance, carcass traits, and immune responses in broiler chickens. Methods: A total of...
Hospitalized pediatric antituberculosis drug induced hepatotoxicity: Experience of an Indonesian referral hospital
Objective: To determine the characteristics and risk factors of pediatric antituberculosis drug induced hepatotoxicity (ADIH) in Dr. Hasan Sadikin Hospital, a referral hospital in West Java, Indonesia. Methods: Medical r...
Nephritic syndrome and anasarca in a case of lymphatic fiariasis: A rare association
Lymphatic filariasis is caused by a nematode, namely, Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis is a spectrum of illness and can manifest as, asymptomatic microfilaria, acute lymphatic f...
Seroprevalence of Toxoplasma among HIV infected and HIV non-infected individuals in North India
Objective: To determine the seroprevalence of Toxoplasma infection in the HIV infected and HIV non-infected individuals in our region, including antenatal women. Methods: Five mL of blood sample was collected from a tota...