DEVELOPMENT OF ANTI-WRINKLE CREAM FROM PUERARIA CANDOLLEI VAR. MIRIFICA (AIRY SHAW AND SUVAT.) NIYOMDHAM, “KWAO KRUA KAO†FOR MENOPAUSAL WOMEN
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 10, Issue 7
Abstract
Objective: The aim of this study was to incorporate Peraria candollei var. mirifica extract into the cream, to evaluate the physical properties and to conduct the skin tests in participants.Methods: Pueraria candollei var. mirifica was extracted with 95% ethanol to obtain crude pueraria extract (PCM). Crude PCM was developed as an anti-wrinkle PCM cream (B) intended for menopausal women. PCM cream was evaluated for stability of pH and viscosity, primary skin irritation, wrinkle reduction and moisturizing as well as customer satisfaction. Cream base (A) and cream purchased from the market (C) were used for comparison. ANOVA post hoc Turkey was used to analyze the variance (p0.05) of the mean comparisons between groups by cluster analysis. Results: The PCM cream appeared as white color, pH was 6.80, and viscosity was 4.069±0.01 Pa. s, as well as physical characteristic and texture, were acceptable and no irritating reaction. PCM cream exhibited a similar level of moisturizer as cream A and C. The PCM cream revealed an ability to decrease the wrinkle surface and wrinkle volume after applied for 7 and 14 d that shows the activity of this product performed from the PCM extract. Satisfaction of PCM cream showed good acceptance.Conclusion: These results suggest that PCM cream has the ability to reduce skin wrinkles. It is a good product for postmenopausal women and may also be of benefit for the general population for protection skin wrinkle.
Authors and Affiliations
Panee Sirisa-ard, Nichakan Peerakam, Nguyen Quoc Huy, Tran Van On, Phung Tuan Long, Aekkhaluck Intharuksa
Keywords
Related Articles
- EP ID EP566211
- DOI 10.22159/ijpps.2018v10i7.24665
- Views 56
- Downloads 0
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDY OF SOME NOVEL FLUORINE BASED 2-AMINOTHIAZOLES
Objectives: To synthesize, characterize and evaluate antimicrobial properties of some novel fluorine based 2-aminothiazoles.Methods: The syntheses of some novel fluorine based 2-aminothiazoles have been described by usin...
AN UPDATE ON NEUROPATHIC PAIN MODELS
An rodent animal model of pain offers a powerful tool in order to understand the mechanism involved in peripheral nerve injury for preclinical study of pain. A battery of neuropathic pain models has been developed to sim...
EVALUATION OF IMPACT OF PHARMACEUTICAL CARE ON IMPROVING KNOWLEDGE AND MEDICATION ADHERENCE IN CKD PATIENTS
Objectives: Evaluation of the impact of pharmaceutical care on improving knowledge and medication adherence in Chronic Kidney Disease (CKD) patients.Methods: Patient data were recorded on a data collection form after inf...
ACUTE DERMAL TOXICITY OF COAL FLY ASH NANOPARTICLES IN VIVO
Objectives: To study the toxicity effects of coal fly ash nanoparticles-induced acute dermal toxicity in Wistar albino rats.Methods: Acute dermal toxicity studies for coal fly ash nanoparticles (CFA-NPs) were conducted i...
A RAPID RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE QUANTITATIVE ESTIMATION OF DABIGATRAN ETEXILATE MESYLATE IN CAPSULES
Objective: To develop a rapid, sensitive, accurate, precise and linear Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method and validate as per ICH guidelines for the quantitative estimation of Dabigatr...