Diabetic Ketoacidosis Clinical Profile, Precipitating Events, Metabolic Abnormalities and Correlation with Treatment Outcome
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 11
Abstract
Abstract: Diabetic ketoacidosis (DKA) is one of the acute metabolic complications of diabetes. DKA occurs in the setting of severe insulin deficiency when low circulating levels of insulin lead not only to hyperglycemia and dehydration but also to the production of ketone body and acidosis. This is a prospective study to assess the clinical profile of diabetic ketoacidosis in patients admitted in general medicine and pediatrics wards/ICU of government medical college Calicut. DKA was seen in both type 1 diabetes and type 2 diabetes. First presentation as DKA was more common among type 1 diabetes. Most common precipitating factors include infections and omission of oral hypoglycemic agents or insulin. Altered sensorium at presentation was an independent predictor of mortality. Low pH, high RBS, hypoponatremia, azotemia, high serum creatinine, hypophosphatemia, hypocalcemia and hypomagnesemia all were associated with increased risk of mortality. Keywords: Diabetic ketoacidosis, Type 1 diabetes mellitus, Type 2 diabetes mellitus
Authors and Affiliations
SreenaSreekumar T, Sugeeth M T, K. G Sajeethkumar, M Vijayakumar
Keywords
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