DIAGNOSIS OF ACUTE LEUKEMIA BY FLOWCYTOMETRY IN POPULATION OF TRIPURA, NORTH-EAST INDIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2014, Vol 1, Issue 10
Abstract
The aim of this study was to diagnose acute leukemia in the population of Tripura using 3-lasers 7-color Flowcytometer. Immunophenotyping was done on peripheral blood samples of acute leukemia cases, by using 2-tube basic AML antibody panel. Samples collected from Regional Cancer Centre, Agartala included in this study 15 Acute Leukemia cases, reported during 2013 & 2014. Among them, 4 were ALL and 11 were AML cases. Out of 15 cases, 12 were adults (9 men and 3 women ranging from 17 to 77 years of age) and 3 were from pediatric patients. A strong correlation (r=0.92) is obtained between the blast cell count by microscopy &flowcytometry. Moreover, this Immunophenotyping procedure on peripheral blood samples also allowed an efficient discrimination between the various cell lineages and facilitated the accurate leukemic blast cell percentage.
Authors and Affiliations
Arup Bhaumik, Shikha Das, Sandeep Roy Sarkar, Payel Chakraborty, Biswajit Chowdhury
Keywords
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- EP ID EP225760
- DOI 10.18410/jebmh/2014/196
- Views 97
- Downloads 0
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