Diagnosis of Diabetes Mellitus Using Glycated Hemoglobin (A1c): The Nigerian Perspective

Journal Title: International Journal of Biochemistry Research & Review - Year 2016, Vol 13, Issue 3

Abstract

Background: Diabetes is an international public health issue. International Expert Committee recommended an alternative diagnostic index testing for diabetes using glycated (A1c). Objective: This study aimed to determine whether A1c test should be used for diagnosing diabetes mellitus in Nigeria. Methods: By assessing the strength of WHO recommendation and the feasibility and resources implication in Nigeria setting. Results: The strength of the recommendation was rated as good by the quality of evidence but not applicable at population level due to high cost and scarce availability of A1c test. Conclusion: The adoption of A1c test as a diagnostic test at present is problematic. Therefore plasma glucose measurements should still be adopted for the diagnosis of Diabetes Mellitus while the A1c assay could be used for monitoring diabetes.

Authors and Affiliations

Tunji Akande

Keywords

Related Articles

Proximate and Mineral Analysis of Methanolic Leaf Extract of Napoleona imperialis (mkpodu)

Napoleona imperialis is an evergreen non-timber plant that has wound healing and antihypertensive effect. The study was undertaken to evaluate the proximate and elemental analyses of the leaf of Napoleona imperialis. The...

The Effect of Aqueous Extract of Buchholzia coriacea Seeds on Some Biochemical Parameters in Normal and Alloxan-induced Diabetic Rats

Aims: To investigate the effect of oral administration of Buchholzia coriacea aqueous seed extract on blood glucose and other biochemical parameters in alloxan-induced diabetic rats and in normal rats. Study Design: Twe...

Some Indices of Carbohydrate Metabolism in Rats Maintained on Heat-treated Vigna unguiculata Husk

The high cost of feed ingredients such as corn is one of the most important factors in livestock production. If agricultural by-products such as Vigna unguiculata husk could replace corn starch in animal feed, the cost o...

Early Detection of Prostate Cancer: Immunoassay for Serum Prostate Specific Antigen (PSA) Tumor Marker

Background: Serum tumor markers are widely used clinically for monitoring response to therapy and detecting cancer recurrence. However, only a limited number of them have been effectively used for the early detection of...

Disulphide Bond Reduction of RNase A by Drug Metosartan a Comparative Study

RNase A is the most experimental protein in the 20th century. Disulphide bonds are necessary for enzymatic action of many proteins as it is also required for this protein. RNaseA kinetic studies is performed with the dru...

Download PDF file
  • EP ID EP351149
  • DOI 10.9734/IJBCRR/2016/27618
  • Views 115
  • Downloads 0

How To Cite

Tunji Akande (2016). Diagnosis of Diabetes Mellitus Using Glycated Hemoglobin (A1c): The Nigerian Perspective. International Journal of Biochemistry Research & Review, 13(3), 1-6. https://www.europub.co.uk/articles/-A-351149