Diagnostic Accuracy of Squash Cytology for Rapid Intraoperative Diagnosis in Tumors of Nervous System
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Introduction: Tumors of the nervous system constitute less than 2% of the cancers globally. They are the second most common form of cancer in children and seventeenth most common in adults. However the morbidity and mortality due to tumors of the nervous system is high. Hence prompt and correct diagnosis is essential for early intervention. In the era of stereotactic biopsies where the amount of tissue is very small, accurate diagnosis is imperative and it can be achieved with squash cytology which is a simple, non-invasive, cost effective and rapid technique. Aim of the study: The aim of the study was to assess the diagnostic accuracy of Squash cytology for rapid Intraoperative diagnosis in tumors of nervous system by comparing histopathology. Materials and methods: This was a prospective study conducted in department of Pathology in a tertiary care teaching medical college hospital for a period of two years. The study subjects were 50 consecutive patients operated for tumors of nervous system in department of neurosurgery. During surgery, small bits of tissue measuring 1-2mm2 were removed and sent in a gauge moistened with saline for squash cytology. The squash smears were correlated with histopathology. Results: The overall diagnostic accuracy of squash cytology in the present study was 82%.Conclusion: Squash cytology in tumors of the nervous system provides an efficient means of pathological assessment which in experienced hands of a neuropathologist will provide high degree of diagnostic accuracy.
Authors and Affiliations
Venkatesh Raju, Jamunarani Srirangaramasamy, Balasubramanian D, Madasamy Balamurugan, Rajesh H, Nishanth Murugan
Keywords
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- EP ID EP374658
- DOI 10.9790/0853-1705072732.
- Views 68
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