Dietary Consumption of Citrullus lanatus can Ameliorate Infertility Potential of Carica papaya Seeds Extract in Male Rats
Journal Title: Biotechnology Journal International - Year 2016, Vol 11, Issue 2
Abstract
Aim: This study examined dietary consumption of Citrullus lanatus as an ameliorative agent against infertility potential of seeds extract of Carica papaya in male wistar rats. Study Design: Eighteen adult male Wistar rats were randomly assigned into three groups of six (n=6): A, B, and C. Group A served as the control group while the other groups served as the treated groups. Place and Duration of Study: This study was carried out in the Animal Holdings of the Department of Anatomy, University of Ilorin, Ilorin, between July, 2014 and October, 2014. Methodology: The Group A animals were given feed and water liberally throughout the study. Group B received 150 mgkg/bwt/d of Carica papaya extract intraperitoneally for 8 weeks, Group C received 150 mgkg/bwt/d of Carica papaya extract intraperitoneally plus Citrullus lanatus orally for 8 weeks. The rats were sacrificed at the end of administration, Testosterone, FSH and LH levels were assayed. Also, semen analysis was carried out to ascertain the level of other parameters. Results: Generally there was significant reduction in the level of Testosterone, FSH and LH in Group B when compared with the Control and Group C. Also, there was significant reduction in the level of sperm count, motility, concentration and morphology in Group B when compared with the Control and Group C. However, there was no significant difference when almost all these parameters were directly compared between Control and Group C. Conclusion: This study has demonstrated that dietary consumption of Citrullus lanatus can ameliorate infertility potential of Carica papaya seeds extract in adult male Wistar rats.
Authors and Affiliations
Nathaniel Ohiemi Amedu, Ukanu Paul Idoko
Keywords
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- EP ID EP237725
- DOI 10.9734/BBJ/2016/22805
- Views 97
- Downloads 0
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