DIFFUSION WEIGHTED IMAGING OF SOFT TISSUE MASSES: CAN APPARENT DIFFUSION COEFFICIENT MEASUREMENT DIFFERENTIATE BETWEEN MALIGNANT AND BENIGN LESIONS ?
Journal Title: Kocatepe Medical Journal - Year 2023, Vol 24, Issue 4
Abstract
OBJECTIVE: To investigate the efficacy of apparent diffusion coefficient (ADC) mapping obtained using the diffusion-weighted imaging (DWI) method in the differentiation of benign and malignant lesions of soft tissue tumors and to establish a quantitative cut-off value for ADC to be used in the differentiation of these lesions. MATERIAL AND METHODS: This retrospective study included a total of 34 patients who underwent DWI due to soft tissue masses and had available histopathological results. According to the pathological results; patients were categorized as having benign and malignant lesions. Measurements were performed using the free hand-drawn region of interest technique. It was investigated whether there was any difference in the evaluated parameters (size, age, gender, and minimum, mean and maximum ADC values). The cut-off value for the parameters evaluated in DWI was determined by the Receiver Operating Characteristic (ROC) analysis. RESULTS: The mean minimum ADC value was 1,28×10-³mm²/s in benign soft tissue masses and 1,00×10-³mm²/s in malignant soft tissue masses. Minimum ADC values differ statistically between the two groups. (p=0,007). A cut-off value of ≤1,01×10-³mm²/s for the minimum ADC allowed for the characterization of soft tissue masses at 78,95% sensitivity and 73,33% specificity. However, the mean and maximum ADC values were not statistically significantly different between the two groups. (p=0,319 and 0,960, respectively). CONCLUSIONS: DWI is an effective method in the evaluation of soft tissue masses in the differentiation of benign and malignant, and taking the cut-off value as ≤1,01×10-³mm²/s in the calculation of minimum ADC will increase the clinical usefulness.
Authors and Affiliations
Mehmet OĞUZMAN Cüneyt ÇALIŞIR Ulukan İNAN
Keywords
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- EP ID EP722687
- DOI https://doi.org/10.18229/kocatepetip.1122866
- Views 55
- Downloads 0
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