DISCORDANCE BETWEEN HIP AND SPINE BONE MINERAL DENSITY USING DXA IN A SAMPLE OF IRAQI ANKYLOSING SPONDYLITIS PEOPLE.
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 2
Abstract
Background: Ankylosing spondylitis (AS) belongs to a family of rheumatic diseases known as spondylarthritides that characteristically cause spinal joint inflammation and bony fusion of the spine. Aim of the study: To measure the discorderance of Osteoporosis in the hip and spinal spines in ankylosing spondylitis in Iraqi people. Patients and methods: A cross sectional study of 70 ankylosing spondylitis patients were are treated with infliximab and etanercpt. All patients have assessment for bone mineral density by DXA for comparism and do another assessment for 35 participants as control. -Those 70 patients were categorized into two groups A and B. the 44 patients in a group A were treated with infliximab while the 26 patients in group B were treated with etanercept. Results: This study showed that the Discordance between spine and hip T-scores was significantly associated with ankylosing spondylitits disease (P < 0.05, table 1, figure 3). the major discordance about (15.7 %) while these in control are zero. The male gender was significantly associated with ankylosing sponfylitits disease (P<0.05). According to (BASDI) and (BASFI) scores at baseline (start of study) and after 6 months, both of (BASDI) and (BASFI) the mean of these scores at start of study and after 6 months did not show a significant differences between the two treatment groups (P > 0.05). Decrease in BASDI and DASFI scores after treatment; BASDI in Etanercept and BASFI for both treatments significantly decreased (P < 0.05). Disease duration (those 5 years) and those (> 5 years), there was no significant difference in Tscores for spine and hip. According to the age and BMI did not show a significant association with AS disease (P > 0.05). Conclusions: There is a positive Correlation between Ankylosing spondylitis and Osteoporosis in [the pelvis and spinal spines]. The patient gender, the activity of the disease and the duration of disease had a positive correlation with the development of Osteoporosis in AS.
Authors and Affiliations
Professor Dr. Sami Salman Shihab
Keywords
Related Articles
- EP ID EP666980
- DOI -
- Views 142
- Downloads 0
ATTITUDES AND OPINION OF HOSPITAL PHARMACISTS TOWARDS EXTEMPORANEOUS COMPOUNDING AND RELATED ISSUES IN KHARTOUM CITY: PART II
Objectives: To examine the frequency, nature and extent of extemporaneous compounding undertaken by Sudanese hospital pharmacists and determine their attitude on aspects related to extemporaneous compounding. Methods: 20...
GENETIC POLYMORPHISM AND SERUM LEVEL OF VASCULAR ENDOTHELIAL GROWTH FACTOR ASSOCIATED WITH FIRST TRIMESTER PREGNANCY OUTCOME IN ICSI PROGRAM
VEGF plays an important role in normal physiological processes that require increased vascularization to bring oxygen and nutrients to tissues, including embryonic development. This study determine the relationship betwe...
COMPARISON OF INTRAOPERATIVE BLOOD LOSS DURING SPINAL SURGERY USING EITHER ISOFLURANE, SEVOFLURANE AND COMBINATION PROPOFOL + REMIFENTANIL AS AN ADJUVANT TO GENERAL ANESTHESIA
Background: Decrease of bleeding is of significant importance in keeping the patient’s hemodynamic stabilized, and also in creating a blood-free field with a good vision for the surgeon. The purpose of this study was to...
CAPECITABINE INDUCED HAND-FOOT SYNDROME IN COLON CANCER PATIENTS -A CASE REPORT OF TWO CASES
Hand Foot Syndrome (HFS), also known as ―Palmoplantar erythrodysesthesia, Acral erythema‖ is a cutaneous reaction caused by certain chemotherapeutic agents that manifests as varying degrees of dysesthesia, painful erythe...
IMPACT OF TEENAGE PREGNANCY ON MATERNAL AND NEONATAL OUTCOMES IN BAGHDAD CITY
Background: Adolescent pregnancy is common health problem still found in both developed and developing countries. Adolescent mother face substantially higher maternal and perinatal morbidity and mortality than adult wome...