Disorders of immunological balance between Th1 and Th2 cells and the role of chosen cytokines in atopic dermatitis
Journal Title: Postępy Dermatologii i Alergologii - Year 2006, Vol 23, Issue 2
Abstract
Atopic dermatitis (AD) is one of the most common diseases in children. This article presents current views on immunological mechanisms that take place in pathogenesis of AD. The role of disturb differentiation of T helper cells and thus promoting subpopulation Th2 cells instead of Th1 cells was shown. Moreover, the role of chosen cytokines, both subpopulations Th1 and Th2, in particular IL-4, IL-5, IL-10, IL-13 and IL-18 was presented. Furthermore, the role of apoptosis as well as participation of CCR4 receptor and its TARC ligand in course of atopic dermatitis were discussed.
Authors and Affiliations
Katarzyna Dzienis, Elżbieta Tryniszewska, Maciej Kaczmarski
Keywords
Related Articles
- EP ID EP83646
- DOI -
- Views 87
- Downloads 0
Zaburzenia równowagi immunologicznej subpopulacji limfocytów Th1 i Th2 oraz rola ich wybranych cytokin w atopowym zapaleniu skóry
Atopowe zapalenie skóry (AZS) jest jedną z najczęstszych chorób skóry występujących u dzieci. W niniejszej pracy zaprezentowano aktualne poglądy dotyczące mechanizmów immunologicznych biorących udział w patomechanizmie A...
The problem of eosinophilia in chronic urticaria
The main purpose of the present study was to analyze peripheral blood eosinophilia phenomenon in patients suffering from chronic urticaria with regard to particular elements of patients’ examination as well as severity o...
Usefulness of chosen molecular techniques in analysis of mutation of NF1 gene in patients with neurofibromatosis type I
Neurofibromatosis is genetic disease with autosomal dominant inheritance. The most frequent form is neurofibromatosis type I (NFI). The onset of the disease is in early childhood or late. Clinical manifestations include...
Role of thoracoscopic sympathectomy in hyperhidrosis of upper limbs - early and late results
Background: Thoracic sympathectomy is a reference treatment of vasoconstrictor disorders of upper extremities. The aim of the study is the presentation was to present the own experience in thoracoscopic sympathectomy in...
Necrotizing fasciitis - life-threatening disease
Necrotising fasciitis is a rare, life-threatening infection of fascia, subcutaneous fat and skin. Necrosis of the tissue is related to ischaemia due to thrombosis of the subcutaneous vessels. It affects more frequently p...