Abstract

Objective: To study the distribution and diversity of species and isolated molecules, according to their structure classes, from Indonesian marine organisms. Methods: This study was performed by using the SciFinder® database, MarinLit and references from relevant articles from 1980 to 2014 which collected all the scientific publications dealing with the isolation of chemical compounds from Indonesian marine macroorganisms and microorganisms. Results: The discovery of novel compounds from Indonesian marine organisms gave us a result of a total of 78 papers. Alkaloids, terpenoids and peptides (84, 67 and 15 new compounds, respectively) represented the three main chemical classes of compounds discovered from Indonesian marine organisms, and together with the other chemical classes showed a range of biological activities. Conclusions: The new marine compounds are mainly from sponges and soft corals. Alkaloids, terpenoids and peptides are the most prolific compounds isolated from Indonesian marine organisms. Most marine natural products from Indonesian organisms have been screened for anticancer or cytotoxicity activities.

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