Distribution of vaccine serotypes among Streptococcus pneumoniae colonizing the upper respiratory tract in healthy pre-school children in south-east Poland
Journal Title: Otolaryngologia Polska - Year 2012, Vol 66, Issue 6
Abstract
Aim: Studies on the distribution of Streptococcus pneumoniae serotypes associated with colo-nization of the upper respiratory tract in young children are currently of general interest because of the impact of the new pneumococcal conjugate vaccines (PCV) on carriage of pneumococci and the incidence of pneumococcal disease. Material and Methods: Therefore, we evaluated the coverage of 10-valent PCV (PCV10) as well as 13-valent PCV(PCV13) of S. pneumoniae serotypes isolated from the upper respiratory tract in healthy pre-school children in south-east Poland. Results: Among the 342 pneumococcal isolates, the serotype coverage by PCV-10 or PCV-13 was 73.7% or 80.1%, respectively. Moreover, 92.4% of the isolates belonged to serotypes included in the old 23-valent polysaccharide vaccine. A clear picture of the distribution of S. pneumoniae serotypes associated with colonization and/or infection in various geographical areas is needed in a light of recommended or routine vaccination.
Authors and Affiliations
Artur Niedzielski, Izabela Korona-Głowniak, Anna Malm, Grażyna Mielnik-Niedzielska
Keywords
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