Do inflammatory factors play a significant role in etiopathogenesis of endometrial cysts? Part 1
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2013, Vol 20, Issue 4
Abstract
Endometriosis is an estrogen-related chronic condition which consists in the implantation and growth of endometrial cells outside the uterine cavity. It has an immune and inflammatory background, and to-date the precise etiopathogenesis of endometrial cysts has not been unequivocally defined. The objective of the study was evaluation of the indicators of the inflammatory state, including RANTES and the levels of C-reactive protein, leukocytes, fibrinogen and iron in the blood serum of patients with endometrial cysts (n=48) and benign ovarian tumours of mature teratoma type (n=38). Statistical analysis was performed using the Mann-Whitney Rank Sum Test. The p values p<0.05 were considered statistically significant. Results: While comparing the results, respectively in groups, the mean levels in blood serum were as follows: RANTES 31,429.79 pg/ml (from 26,576.6 – 99,605.00) vs. 26,988.72 pg/ml (from 26,013.58 – 113,435.00) for p=0.428; CRP and WBC 2.13 vs. 1.54 mg/l; p=0.076 and 5.35 vs. 6.7; p=0.029; fibrinogen 3.12 vs. 2.57 mg%; p<0.001); iron level 87.20 vs. 78.01 ug/dl for p=0.430, and CA-125 36.50 vs. 15.08 U/ml; p<0.001). Conclusions: Statistically significant differences were observed in the levels of WBC, fibrynogen and CA-125 in blood serum. Therefore, the role of the inflammatory factor in the etiopathogenesis of endometrial cysts still remains unexplained, and the presented study may emerge as pioneer investigations in the area of etiology of endometriosis.
Authors and Affiliations
Karolina Chmaj-Wierzchowska, Małgorzata Kampioni, Maciej Wilczak, Tomasz Opala
Keywords
Related Articles
- EP ID EP80720
- DOI -
- Views 155
- Downloads 0
Salt caves as simulation of natural environment and significance of halotherapy
Introduction. Human activity usually leads to a deterioration in air quality; therefore, searching for places that simulate an environment without pollution is important. Artificial salt caves play crucial role, as a kin...
Comprehensive rehabilitation in chronic heart failure
Chronic heart failure (CHF) is a complex disease process connected with cardiovascular system as well as other organs and skeletal muscles. In connection with the above, cardiac rehabilitation, consisting of exercise tra...
Biological and environemntal conditionings for a sperm DNA fragmentation
The objective of the presented study was determination of the effect of selected agents on sperm DNA fragmentation – superoxide dismutase in seminal plasma, the patients’ age, and burdening with the tobacco smoking habit...
Urban vs. rural patients. Differences in stage and overall survival among patients treated surgically for lung cancer
Introduction. Besides the undoubted influence of risk factors on morbidity and survival time, there are also other environmental factors, such as awareness of the prevalence of risk factors and the availability of modern...
<strong><em>Borrelia burgdorferi</em></strong><strong> sensu lato as activators of the complement system in <em>in vitro</em> model.</strong>
Introduction. The following parameters were analyzed: C5a, which is significant in classical and alternative pathways of the complement system activation, and factor H, the major function of which is to regulate the alte...