DO PLATELET INDICES PLAY A ROLE WITH RESPECT TO PLATELET COUNT AND INFECTIONS?
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 44
Abstract
BACKGROUND Platelet an essential constituent of blood plays an important role in coagulation, thrombosis, inflammation and maintains the integrity of vascular endothelial cells. Platelet indices like Plateletcrit (PCT), Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Platelet Large Cell Ratio (P-LCR) are a group of derived platelet parameters obtained as a part of automatic complete blood count. Various infections and metabolic disorders cause variations in the platelet counts and platelet indices. This study aims to summarise the potential role of platelets and platelet indices as risk markers for early screening of infections. MATERIALS AND METHODS This is a descriptive comparative study. The present study included 103 cases and they were subtyped into four groups, i.e. tuberculosis, dengue, malaria and chronic liver disease. Platelet indices in different infections were obtained. RESULTS PDW was normal in dengue, malaria and chronic liver disease, but decreased in tuberculosis. MPV was normal in malaria, dengue and chronic liver disease, but MPV was low in tuberculosis. P-LCR was increased in dengue and malaria, decreased in tuberculosis and normal in chronic liver disease. CONCLUSION Platelet indices have been valuable indicators of illness severity and effective predictors of clinical outcomes. Platelet indices could be easily measured from routine blood examination that is inexpensive and repeatable. This provides a convenient stratification tool in infections.
Authors and Affiliations
Rachana Kiran Koppalkar, Purnima S. Rao, Sandhya I, Prithal G
Keywords
Related Articles
- EP ID EP549255
- DOI 10.14260/jemds/2018/1061
- Views 94
- Downloads 0
A STUDY OF FASTING AND POSTPRANDIAL LIPID ABNORMALITIES IN TYPE 2 DIABETES MELLITUS
AIM 1. To assess the nature of fasting dyslipidaemia in type 2 diabetes mellitus and correlate the same with severity and duration of diabetes. 2. To assess the postprandial lipid abnormalities in type 2 diabete...
EVALUATION OF PREANALYTICAL ERRORS IN CLINICAL BIOCHEMISTRY LABORATORY IN A TERTIARY CARE HOSPITAL IN KOLKATA
BACKGROUND Accurate laboratory results are vital for patients’ safety. Errors in laboratory may occur in the pre-analytical, analytical and post analytical phase. In the present study, we tried to identify the types of t...
AN IN-VITRO STEREOMICROSCOPIC COMPARISON OF PROTAPER RETREATMENT, MTWO RETREATMENT AND HEDSTROM FILES IN REMOVAL OF AN EPOXY RESIN-BASED SEALER AND MTABASED SALICYLATE RESIN SEALER DURING ENDODONTIC RETREATMENT
BACKGROUND Success of non-surgical endodontic retreatment is dependent on the effective removal of root canal filling material. Not many studies have compared the effectiveness of different file systems in removing root...
MISSED MALIGNANCY IN MIXED BILATERAL BENIGN BREAST LESIONS- A CLINICAL STUDY
BACKGROUND Though breast diseases even in benign status poses considerable anxiety and fear to the suffering woman and to her blood relatives, this leads to extensive investigative modalities in benign breast diseases in...
ISOLATED LICHEN PLANUS OF THE CONJUNCTIVA WITH ASSOCIATED BOWEN’S DISEASE: A CASE REPORT
Bowen’s disease is an intraepithelial neoplasm involving the squamous epithelium, commonly occuring in the genital region. Rarely, it is also observed at skin in other anatomical location. Lichen planus is chronic de...