Docking and QSAR based screening of some naturally occurring diterpenes as inhibitors of angiotensin converting enzyme (ACE) against cardiovascular diseases
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2014, Vol 2, Issue 11
Abstract
Many plants have been listed in the traditional systems of medicine and some of these are providing comprehensive relief to the people suffering from cardio-vascular diseases (CVD) and are recognized for their ability to produce secondary metabolites. Secondary metabolites obtained from different plants have been the starting material for designing different drugs. Naturally occurring diterpenes are the secondary metabolites that show myriad varieties of pharmacological activities. These diterpenes exert cardiovascular actions and paved the path towards development of cardioprotective formulations.
Authors and Affiliations
Monjur Ahmed Laskar and Manabendra Dutta Choudhury*| Bioinformatics Centre, Assam University, Silchar – 788011, Assam, India.
Keywords
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