Early predictive value of serum CRP/ALB and PCT/ALB for the severity of acute pancreatitis
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 5
Abstract
<b>Objective</b> To explore the early predictive value of the C-reactive protein to albumin ratio (CRP/ALB) and procalcitonin to albumin ratio (PCT/ALB) for the severity of acute pancreatitis (AP). <b>Methods</b> A retrospective analysis was conducted on the clinical data of 133 patients with AP who were hospitalized at the Second Affiliated Hospital of Zhengzhou University from January 2020 to December 2022.Among them, there were 85 cases in the non-severe acute pancreatitis (NSAP) group and 48 cases in the severe acute pancreatitis (SAP) group. Univariate analysis of variance was performed on the age, total hospital stays, ICU admission rate, amylase, white blood cell (WBC) count, hematocrit (HCT), Ca2+, serum creatinine (Cr), blood urea nitrogen (BUN), D-dimer, serum procalcitonin (PCT), CRP, serum albumin (ALB), PCT/ALB, CRP/ALB in two groups to screen the indicators related to the severity of AP. Subsequently, ROC curve analysis and binary logistic regression analysis were condacted on the selected indicators. <b>Results</b> The ROC curve analysis showed that the area under the curve of CRP, CRP/ALB, PCT, and PCT/ALB were 0.793, 0.804, 0.869, and 0.881, respectively. The logistic regression analysis showed that CRP/ALB［OR=1.685,95%CI(1.293,2.195)］ and PCT/ALB［OR=1.255,95%CI(1.052,1.497)］ were independent risk factors for predicting the severity of early AP. <b>Conclusion</b> The higher the CRP/ALB and PCT/ALB, the greater the likelihood that AP patients will develop into severe illness, and both are positively correlated with the severity of AP in patients.
Authors and Affiliations
ZHU Lingjuan, CUI Jing
Keywords
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- EP ID EP736342
- DOI 10.13429/j.cnki.cjcr.2024.05.022
- Views 54
- Downloads 1
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