Editorial office panel IOSR Journal of Dental and Medical Sciences (IOSR-JD
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Objective: Tinnitus is a very common complaint and affects 7% of population and has been associated with a range of physical and emotional disorders. There are several modalities of treating tinnitus, but with doubtful response. For patients with no response to conventional treatment studies have proven various drugs injected intra-tympanically proved effective. This study aims at comparing the effectiveness of intra-tympanic Dexamethasone over 4% Lignocaine in treatment of tinnitus by comparing of pre-treatment OAE's, THI and VAS with post treatment OAE's, THI and VAS of patients with tinnitus. Materials and Methods: Seventy two patients enrolled for study was randomly assigned to two drug groups were evaluated and Intra-tympanic injection of the drug (4% Lignocaine or Dexamethasone) was done. Pre injection and post injection Tinnitus Handicap Inventory (THI), Visual Analogue Scale (Loudness/ Annoyance) for Tinnitus (VAS-L/VAS-A) and OtoAcoustic Emissions (OAE) were also noted. Comparative multivariate analyses between indicator factors and tinnitus were conducted. Results: The pre-injection THI scores, VAS-L/VAS-A scores and OAE’s recorded and Post injection 30 minutes, 1 day, and 1 week THI scores, VAS-L/VAS-A scores and OAE’s recorded showed significant reduction in these levels for both the group. But the 1 month post injection recordings of THI scores, VAS-L/VAS-A scores and OAE’s showed reduction in the values of dexamethasone group but increases to the near pre-injection levels in lignocaine group. Conclusion: Both the drugs are proven to be effective in treating tinnitus but in our study comparing the effects of these two treatment modalities, intra-tympanic dexamethasone injection has a better results compared to intratympanic 4% lignocaine injection- symptomatically and complication wise.
Authors and Affiliations
Prof. Dr. V. Saravanan MS. , Prof. Dr. A. R. Ali Sulthan MS. , Dr. Anish karthick
Keywords
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