Effect of a high amino acid diet on antioxidant barrier parameters of rat skin.
Journal Title: Progress in Health Sciences - Year 2019, Vol 1, Issue
Abstract
<b>Introduction:</b> Oxidative stress is largely responsible for numerous skin complications that occur in the course of various diseases as well as accelerated skin aging. A high amino acid diet, supplemented with whey protein concentrate (WPC), is well-balanced and has well-absorbing proteins, which are an ideal source of essential amino acids. <br/><b>Purpose:</b> To assess what changes will occur in the antioxidant barrier of unharmed skin of rats on a high amino acid diet. <br/><b>Materials and methods:</b> The study was conducted on sexually mature male Wistar rats (160-180g): 1. control (standard feed), 2. high amino acid diet (WPC-80 80% whey protein) administered for 7 days at a dose of 0.3g/kg of body weight, 3. WPC-80 for 7 days at a dose of 0.5g/kg of body weight, 4. WPC-80 for 14 days at a dose of 0.3g/kg of body weight, 5. WPC-80 for 14 days at a dose of 0.5g/kg of body weight. Total antioxidant capacity, total oxidative status and oxidative stress index were determined. <br/>Results:</b> Enrichment of a standard diet with WPC-80 did not affect the total oxidative status of undamaged healthy rat skin. This study shows that a diet rich in amino acids in rats caused an increase in total antioxidant capacity, but statistically significant values were obtained after 14 days of administering WPC at a dose of 0.5mg/kg of body weight. <br/><b>Conclusions:</b> Enrichment of a standard diet with WPC-80 strengthens the antioxidant barrier in unwounded healthy rat skin.<br/><br/>
Authors and Affiliations
M. Niczyporuk, K. Grądzka, H. Car
Keywords
Related Articles
- EP ID EP641346
- DOI 10.5604/01.3001.0013.3695
- Views 82
- Downloads 0
Detection of PRL-3 protein in the preoperative serum of patients with colorectal cancer
Purpose: The aim of study was to detect PRL-3 protein in sera of patients with colorectal cancer. Methods: The study group consisted of 22 patients with colorectal carcinoma and 10 healthy controls. The serum concentrati...
Mobile phone owners' health behaviors
Introduction: The consistently growing number of mobile phone users has contributed to increasing interest in the effects of mobile phones on human health. Purpose: To assess the preferred health behaviors of mobile phon...
Integrated management of childhood illness: Bringing treatment closer to home
Globally, the main target of all child health programs is to ensure a reduction in infant/under-five mortality. Globally the progress has been observed in reducing child mortality rate the average annual rate of reductio...
Polish and Belaursian students’ attitudes toward other nations
Introduction: Approximately 7,000 different ethnic groups and nations inhabit the earth, and most of the tensions among people stem from prejudice and intolerance. Purpose: To assess a student perception of foreign nati...
An open, multicenter flexible dose escalation study to evaluate the efficacy and safety of sildenafil administered as required to male patients with erectile dysfunction
Objective: To evaluate the efficacy, satisfaction, safety and tolerability of sildenafil taken as prescribed prior to anticipated sexual activity in male outpatients with erectile dysfunction (ED). Materials and m...