Effect of Advanced Fibrosis Presence on Adherence to Hepatocellular Carcinoma Surveillance in Chronic Hepatitis C Patients with Sustained Virologic Response
Journal Title: Viral Hepatitis Journal - Year 2020, Vol 26, Issue 1
Abstract
Objectives: Although hepatocellular carcinoma (HCC) screening is accepted as standard care in patients with chronic hepatitis C (CHC) diagnosis, sustained viral response (SVR) has been obtained by treatment and it is not certain what the condition is in the group of patients with advanced fibrosis who are at increased risk for developing HCC before treatment. In this cohort of patients, the practice of HCC was intended to be evaluated in real life conditions. Materials and Methods: Between 2007-2019, the information cards of the patients diagnosed with CHC were retrospectively examined. Patients with advanced fibrosis,prior the treatment, who had obtained SVR were enrolled in the study. HCC screening was defined as alpha-fetoprotein testing and liver imaging combined. HCC surveillance every 6 months or more was defined as compliance with screening guidelines. Results: The number of patients in the study was 83 (n=32, cirrhosis). During the follow-up period, the median was 35 (13-124) months, 24 (6.1%) patients were diagnosed with HCC. 48.2% (n=40) of the patients observed screening guidelines, while 22.9% (n=19) did not follow the guidelines; 28.9% (n=24) did not have screening. Conclusion: HCC screening in CHC patients with advanced fibrosis is not carried out in accordance with the guidelines.
Authors and Affiliations
Göktuğ Şirin, Sadettin Hülagü
Keywords
Related Articles
- EP ID EP684578
- DOI 10.4274/vhd.galenos.2020.2020.0002
- Views 119
- Downloads 0
How Aware are We of the Immune Status of Hepatitis B and Hepatitis A in Chronic Hepatitis C Patients? A Multicenter Retrospective Study from Turkey
Objectives: Patients with chronic hepatitis C virus (HCV) infection and superinfection by hepatitis A or hepatitis B virus have higher morbidity and mortality when compared with those without HCV infection. The aim of th...
Relationship Between Viral Load and Prohepcidin Levels in Chronic Hepatitis B Patients
No summary
Evaluation of Hepatitis C Virus Genotype Results in İzmir Atatürk Training and Research Hospital
Objectives: The aim was to support both the clinical treatment and management and also to contribute to the epidemiological understanding of the hepatitis C virüs (HCV) genotype in our region. Materials and Methods: HCV...
Molecular Characterization of Hepatitis B Virus Strains Isolated from Chronic Hepatitis B Patients in Southeastern Region of Turkey
Objectives: The aim of the present study was to assess the molecular aspects of HBV strains isolated from chronic hepatitis B (CHB) patients, in the Southeastern region of Turkey. Materials and Methods: The study involv...
Non-hodgkin Lymphoma Developing After Discontinuation of Direct-acting Antiviral Treatment for Hepatitis C: A Case Report
Today, direct-acting antivirals (DAA) are the main treatment options for hepatitis C infection. However, whether malignancy risk is increased after DAA treatment is a matter of debate. Conflicting results have been repor...