EFFECT OF ANTIOXIDANTS AND ANTIBIOTICS ON LEVELS OF SEMINAL OXIDATIVE STRESS IN LEUKOCYTOSPERMIC INFERTILE MEN
Journal Title: Indian Journal of Clinical Biochemistry - Year 2006, Vol 21, Issue 1
Abstract
Defective sperm function is the most common cause of infertility. A prospective study was carried out to correlate the concentration of nitrite (the stable metabolite of nitric oxide) in seminal plasma with leukocytospermia, and sperm membrane integrity. Total Fifty-seven normozoospermic subjects with and without leukocytospermia visiting the Infertility clinic at KH and MRC, Karad, were included in the present study. Semen samples were checked for sperm concentration, total sperm count, sperm motility, seminal leukocyte concentration and sperm membrane integrity as Hypoosmotic Swelling Test. Similarly the concentration of nitrite in seminal plasma was measured by Griess reaction and total antioxidant power measured as ferric reducing ability of plasma. The concentration of nitrite in seminal plasma was found to be raised with significantly increased leukocyte concentration in semen. Also significantly lowered levels of total antioxidant power along with defective sperm function was observed. Our results suggest that supplementary treatment of antioxidants with antibiotic for leukocytospermic infertile male patients may improve the sperm membrane integrity.
Authors and Affiliations
Sunil B. Yadav1, Adinath N. Suryakar2, Anil D. Huddedar3 and Pramod S. Shukla1
Keywords
Related Articles
- EP ID EP107458
- DOI -
- Views 127
- Downloads 0
IN VITRO INHIBITION OF LIPID PEROXIDATION IN FISH BY TURMERIC (CURCUMA LONGA)
The beneficial effects of ω-3 fatty acids on human health have been well documented. Fish and fish oils are the richest sources of ω-3 fatty acids. However, due to their high degree of unsaturation, they are highly sus...
EFFECT OF INCREASING DURATION OF DIABETES MELLITUS TYPE 2 ON GLYCATED HEMOGLOBIN AND INSULIN SENSITIVITY
Non-insulin dependent diabetes mellitus (NIDDM) is the most rapidly growing chronic metabolic disorder in the world. With advancement in the age and duration of diabetes there is a gradual tendency for the level of blo...
THE INFLUENCE OF TOBACCO SMOKING ON HUMORAL IMMUNE RESPONSE IN INSULIN DEPENDENT DIABETIC PREGNANCY
Tobacco smoking products have a heavy impact on the public health of developed as well as non-developed countries by being a main etiologic factor for the induction of cardiovascular diseases and tobacco-related cancer...
EFFECTS OF SHORT-TERM HORMONE REPLACEMENT ON ATHEROGENIC INDICES IN INDIAN POSTMENOPAUSAL WOMEN
Indian ethnicity by itself is a strong risk factor for development of CAD in Indian postmenopausal women due to lower HDL levels as compared to Whites and women of oriental origin. We evaluated and compared the short-...
SIALIC ACID IN CARDIOVASCULAR DISEASES
Sialic acid, the acylated derivatives of 9-carbon sugar neuraminic acid, present as terminal component of oligosaccharide chains of many glycoproteins and glycolipids, has been recognized to be involved in the regulati...