Effect of body temperature on residual neuromuscular blockade of intermediate-acting neuromuscular blocking agents
Journal Title: Ege Tıp Dergisi - Year 2016, Vol 55, Issue 2
Abstract
Aim: Aim of this study was to compare the rates of residual neuromuscular block in patients at different postoperative body temperatures. We also investigated incidence of early postoperative residual neuromuscular block with intermediate acting neuromuscular blocking agents and the factors affecting early postoperative residual neuromuscular block with intermediate acting neuromuscular blocking agents. Material and Methods: Two hundred and sixty-eight patients who underwent surgery under general anesthesia were enrolled in this study. Patients were monitored with an acceleromyograph from the moment of admission to post anesthesia care unit. In addition to Train of Four (TOF) measurements, patients' clinical findings (tongue depressor test, hand squeezing, existence of diplopia, ability to swallow, ability to lift head and legs for 5 seconds) were monitored and recorded. Patients body temperatures are measured with a tympanic thermometer and residual neuromuscular block at different body temperatures were compared. Results: The incidence of residual neuromuscular block was 48.9%. Univariate analysis of the data showed that surgical duration, maintenance dose administration, administration of reversal agent and body temperature were significantly relevant with residual neuromuscular block. There weren't any statistically significant difference between TOF values of patients with body temperatures lower or higher than 35ºC who were administered either one of the 3 neuromuscular blocking agents utilized in this study. Conclusion: We conclude that choice of intermediate acting neuromuscular blocking agent has no influence on residual neuromuscular block in patients with both intraoperative and postoperative mild hypothermia.
Authors and Affiliations
Sermin Karaarslan, Mustafa Gönüllü, Zeki Tuncel Tekgül, Ergin Alaygut, Yücel Karaman
Keywords
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- EP ID EP340432
- DOI 10.19161/etd.344183
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