Effect of differential endometrial injury timing on frozen-thawed embryo transfer pregnancy outcomes
Journal Title: Clinical and Experimental Obstetrics & Gynecology - Year 2019, Vol 46, Issue 1
Abstract
Objective: To explore whether differential endometrial injury (EI) timing prior to a frozen-thawed embryo transfer (FET) cycle yields similar improvements in pregnancy outcomes. Materials and Methods: A total of 688 women underwent consecutive FET cycles. Based on their desire to undergo differentially timed EI or not, patients were divided into four groups: on the 3rd–5th day of the menstrual phase of the FET cycle (n = 308), on the 3rd–5th day of the menstrual phase preceding the FET cycle (n = 78), during the luteal phase of the cycle preceding the FET cycle (n = 83), and no intervention (n = 219). Results: The pregnancy outcomes in the four groups were significantly different. The chemical pregnancy, clinical pregnancy, implantation, and live birth rates of patients who underwent EI on the 3rd–5th day of the menstrual phase preceding the FET cycle were the highest, followed by those who underwent EI on the 3rd–5th day of the menstrual phase of the FET cycle. The lowest rates were those during the luteal phase of the cycle preceding the FET cycle and patients who had no interventions, which were similar. Conclusions: Differential EI timing resulted in differential improvement of pregnancy outcomes for FET.
Authors and Affiliations
Jianping Zhang, Fang Yang, Yaoqin Wang, Yonglian Wang, Hongmei Liang, Xueqing Wu
Keywords
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- EP ID EP618526
- DOI 10.12891/ceog4152.2019
- Views 66
- Downloads 0
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