Effect of Intravenous Zoledronic Acid on Bone Mineral Density in Geraitrics
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Osteoporosis is a systemic skeletal progressive disease with multiple factors involved in its causation. A huge prevalence rate, a substantial morbidity and a significant mortality risk, is of specific concern especially in elderly. Among the various modalities of evaluation, dual energy x-ray absorptiometry is the one used here for obtaining bone mineral density and T-scores of the patients. In this study the effect of zoledronic acid in improving bone mineral density over an year is seen, in elderly population of Rajasthan, and a significant improvement was seen with minimal side effects, which can be managed conservatively. AIM: To study the effect of Intravenous Zoledronic acid on BMD in Geriatric patients with the objective to present and compare the profile of BMD and T-score < 2.5 in geriatric patients attending at orthopedic department of S.M.S. hospital, Jaipur. Material and methods: It is a hospital based prospective before and after interventional study. Sample size was calculated 81 subjects at 0.05 alpha error and power 80% assuming difference of means to be detected in BMD is 0.01 with SD 0.038.
Authors and Affiliations
Anurag Sharma, Amit K. Jain, R. C. Meena, Lokpal Singh Bhati, Laxman Chaudhary
Keywords
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- DOI 10.9790/0853-1803092934.
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