Abstract

Background: Through the last recent years many researches started to investigate the properties of Aloe vera. Aloe vera proved to have wide ranges of activities in different fields of medicine. Objective: The study was conducted to evaluate the antifungal activity of Aloe Vera extract in aqueous and alcoholic solvents against Candida albicans species which isolated from dentures of patients with denture stomatitis. Material Method: Twenty six patients with denture stomatitis, Candida albicans were isolated and identified by using a routine microbiology method which includes the microscopically examination, culture and biochemical test by using API test. Preparation of aloe Vera extracts (watery and alcoholic) in different concentration was done, then the antifungal activity of aloe Vera for both extracts types were tested by using candida colony count after cultivated on culture media and agar well diffusion method to estimation the diameters of inhibition zone in different concentration. Results: The results revealed that the Aloe Vera contained substantial antimicrobial efficacy. The alcoholic extracts induce significant inhibition in growth of candida albicans in comparison to aqueous one and the inhibitory effect was found to be variable with the applied concentration. The candida species that isolated from nylon dentures was more sensitive than that isolated from acrylic dentures to Olea extract of different forms. Conclusion: Olea Vera extracts in high concentration have a reliable antifungal activity, alcoholic extract of Olea was more effective than aqueous type and can be used as an alternative to traditional antiseptic solution.

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