Effect of Pomegranate (Punica granatum L.) Seed Oil on Markers of Oxidative Stress Induced by Carbon Tetrachloride in Wistar Rats
Journal Title: International Journal of Food Science, Nutrition and Dietetics (IJFS) - Year 2015, Vol 0, Issue 5
Abstract
The pomegranate seed oil (PSO) presents a high content of the punicic acid (PA), which is a conjugated isomer of α-linolenic acid (CLNA). Conjugated fatty acids have increasingly attracted scientific interest because of their several potential health benefits, including antioxidant activity. The aim of this study was to evaluate the supplementation effect of PSO on oxidative stress markers in rats subjected to liver injury by carbon tetrachloride (CCl4). Animals were supplemented with PSO at concentrations of 2% and 4%, for 21 days, and then subjected to liver injury induced by CCl4. The PSO supplementation reduced serum aminotransferase enzymes and the percentage of liver damage induced by CCl4. Conversely, PSO supplementation increased the lipid hydroperoxides levels in the liver. Overall, these results suggest that supplementation with PSO is not capable of attenuating markers of oxidative stress caused by CCl4.
Authors and Affiliations
Illana Louise Pereira de Melo
Keywords
Related Articles
- EP ID EP201928
- DOI 10.19070/2326-3350-SI05001
- Views 112
- Downloads 0
Nutritional and Safety Evaluation of Heat-Stabilized Rice Bran for Supplementary Feeding of Malnourished Children in Kenya
Rice bran is a by-product of rice milling that has been primarily used in animal feed negating its potential for human consumption. The aim of this study was to evaluate the application of rice bran to aid in managing in...
Nutrition Module Intervention to Improve Nutrition Knowledge, Attitude and Practice of Trainers for Persons with Disabilities in Rehabilitation Centers in Malaysia
Introduction: Other than parents, primary care providers such as community workers and rehabilitation service personnel are also important nutritional gatekeepers for persons with disabilities (PWD). Good nutrition manag...
Evaluating Effects of an Oral Green Tea Extract, Polyphenon E, on Tissue Biomarkers, Using Reverse Phase Protein Array in Women with Operable Breast Cancer
Experimental data support potential anti-tumor effects of green tea in breast cancer, yet limited data exists in human intervention trials. We conducted a phase 0 single-arm trial in women with newly diagnosed operable b...
Measurement Of Activity Concentrations Of 226Ra, 232Th, 40K And 137Cs In Some Common Spices Consumed By Inhabitants In Accra Metropolis, Ghana.
A spice is a vegetable substance of indigenous or exotic origin which is or has a hot, pigment taste, used to enhance taste of foods or to add to them the stimulant ingredients contained in them. Knowledge of radioactivi...
Microbiological Quality and Safety of Energy Drink Available in the Local Markets in Saudi Arabia
A Energy drinks have become a popular beverage worldwide. The global market for energy drink has gained momentum in the past decade, and demand is increasing every year. The objective of this study was to evaluate the mi...