Effect of two different doses of Dexmedetomidine on hemodynamic responses during tracheal extubation
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 8, Issue 3
Abstract
Background: Haemodynamic responses to tracheal extubation have always been of importance to the anaesthesiologist.Different concentrations of dexmedetomidine ranging from 0.25 µg/kg to 1.0 µg/kg intravenously as a bolus, have been studied for attenuation of pressor responses to extubation and intubation. Aim: To study the effects of two different doses of dexmedetomidine on hemodynamic responses during tracheal extubation. Material and Methods: A total of 66 patients undergoing surgery under general Anaesthesia in our hospital were randomly divided into 2 groups: Group-D1: Dexmedetomidine (0.25 µg/kg) group –33 patients; Group-D2: Dexmedetomidine (0.5 µg/kg) group – 33 patients. Results: The heart rate was significantly lower in D2 group at 10 minutes after starting of study drug, during extubation and till 15 minutes after extubation (p<0.05).The SBP and DBP was significantly lower in D2 group during extubation and till 15 minutes after extubation (p<0.05). Conclusion: Dexmedetomidine in 0.5 mcg/kg dose is optimum to attenuate the extubation response as compared to low dose i.e., 0.25 mcg/kg.
Authors and Affiliations
Pradeep Shivaji Raut, Ghanshyam Jadhav
Dexmedetomidine as an adjuvant to ropivacaine in supra-clavicular brachial plexus block
Background and Aim: The advantages of a supraclavicular technique over other brachial plexus block approaches are its rapid onset and complete and predictable anesthesia for entire upper extremity and particularly, hand...
A study of haemodynamic response on low dose dexmedetomidine infusion in laparoscopic surgery
Background: Dexmedetomidine is a potent and highly selective α-2 adrenoceptor agonist with sympatholytic, sedative, amnestic and analgesic properties which has been described as a useful and safe adjunct in many clinical...
A randomised clinical trial to compare the butorphanol and nalbuphine as adjuvants in ultrasound guided supraclavicular brachial plexus block
Background: Supraclavicular brachial plexus block provides complete anaesthesia for surgeries of upper limbs especially below the mid humerus.Using ultrasound for blocks not only increases the success rate but also reduc...
Anesthetic management of a patient with insulinoma
Insulinomas are an uncommon cause for recurrent hypoglycemia. Surgical resection is the definitive treatment. We present a case of a36-year-old male patient diagnosed with insulinoma and right parathyroid adenoma who had...
Study of various technical difficulties encountered during the administration of quicke's needle 22 and 26 for spinal anesthesia
Background: Neuraxial blocks, such as spinal and epidural block, are common practice in anesthesia and are widely used for a number of surgical and endoscopic procedures. Aims and Objectives: To Study various technical d...