Effect of vitamin D3 supplementation on episodes of acute respiratory tract infection in exclusively breast fed infants- a hospital based study.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 5
Abstract
Background : In humans, vitamin D is synthesized in the skin from exposure to sunlight or can be obtained through dietary intake that functions as a steroidal hormone after conversion in the renal tubule to its active form 1-25-hydroxyvitamin D(25(OH)D) by 1-alpha-hydroxylase enzyme Methods: A randomized control study was conducted at Department of Pediatrics, MGM hospital, Navi Mumbai after ethical clearance, during period of 7 months from 1st march 2014 to 30 September 2014 and followed up till 30 June 2015. A final sample of 200 exclusively breast fed newborns, were then randomized into two groups: Group A: Placebo group and; Group B: Vitamin D3 supplementation group (400IUOD). Both the groups were followed up at regular intervals (1.5, 2.5, 3.5, 6 and 9 months). At each visit episodes of acute respiratory tract infections were recorded. Statistical analysis was done by SPSS17. Data were analyzed by unpaired t- test. Results: Mean number of acute respiratory infection episodes (3.44 vs 0.85; Median 4 vs 1) were significantly more in babies of placebo group as compared to Vitamin D group. Conclusion: Frequency of Acute respiratory infection episodes were significantly less in vitamin D supplemented group as compared to Placebo group.
Authors and Affiliations
Dr. Pallavi Sharma
Keywords
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